L-Nil

L-Nil

SCHEMBL322091

CC(=N)NCCCC[C@H](N)C(=O)O

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ARG2 P78540 4/20 0.50
ARG1 P05089 3/20 0.50
GSR P00390 1/20 0.50
OTC P00480 1/20 0.49
NOS2 P35228 6/20 0.49
NOS1 P29475 5/20 0.49
NOS3 P29474 4/20 0.49
CYP1A2 P05177 1/20 0.49
CYP3A4 P08684 1/20 0.49
TSHR P16473 1/20 0.49
BLM P54132 1/20 0.47
DPP7 Q9UHL4 1/20 0.46
MEN1 O00255 1/20 0.46
CYP2C19 P33261 1/20 0.46
KMT2A Q03164 1/20 0.46
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
NOD1 Q9Y239 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Nil SCHEMBL31540966 1.00 ARG2 (0.50) ARG2ARG1GSROTCNOS2
L-Nil SCHEMBL934874 1.00 ARG2 (0.50) ARG2ARG1GSROTCNOS2
L-Nil SCHEMBL677147 0.98 ARG2 (0.51) ARG2ARG1GSROTCNOS2
L-Nil SCHEMBL1321685 0.98 ARG2 (0.51) ARG2ARG1GSROTCNOS2
SCHEMBL8065968 0.98 NOS2 (0.50) ARG2ARG1GSROTCNOS2
L-Nil SCHEMBL7977021 0.98 ARG2 (0.51) ARG2ARG1GSROTCNOS2
L-Nil SCHEMBL7974005 0.98 ARG2 (0.51) ARG2ARG1GSROTCNOS2
Hydrochloric Acid SCHEMBL8470176 0.97 ARG2 (0.50) ARG2ARG1GSROTCNOS2
L-Nio SCHEMBL4424485 0.95 OTC (0.54) ARG2ARG1GSROTCNOS2
L-Nio SCHEMBL1569333 0.95 OTC (0.54) ARG2ARG1GSROTCNOS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 694 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4744663-A2 SKIN COMPOSITION Eaderm Co., Ltd. (JP) 2026-05-20 EP claimed
EP-3338813-B2 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2026-04-15 EP claimed
EP-4709378-A1 COMPOUNDS FOR NOS-RELATED CANCERS AND METHODS OF USE Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-03-18 EP claimed
EP-3558399-B2 MULTI-LAYER WOUND CARE PRODUCT WITH PERFORATED RELEASE LAYER BSN MEDICAL GMBH (DE) 2026-01-14 EP claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
US-20250276085-A1 SYNTHETIC MULTIDOMAIN PEPTIDE BIOMATERIALS THAT INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE WILLIAM MARSH RICE UNIVERSITY (US) 2025-09-04 US claimed
US-12251449-B2 Synthetic multidomain peptide biomaterials that inhibit inducible nitric oxide synthase WILLIAM MARSH RICE UNIVERSITY (US) 2025-03-18 US claimed
US-12163161-B2 In vitro method for identifying thoracic aortic aneurysms (TAA) in a subject CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.) (ES) 2024-12-10 US claimed
WO-2024231899-A1 COMPOUNDS FOR NOS-RELATED CANCERS AND METHODS OF USE YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-11-14 WO claimed
WO-2024224296-A2 TARGETED PHARMACEUTICAL COMPOSITIONS TO TREAT NEUROLOGICAL CONDITIONS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. (IL) 2024-10-31 WO claimed
WO-2004024132-A2 USE OF NO-SIGNAL CASCADE MODULATORS AND PHARMACEUTICAL COMPOSITION Eberhard-Karls-Universität Tübingen (DE) 2004-03-25 WO claimed
WO-2004010894-A2 OPHTHALMOLOGIC IRRIGATION SOLUTIONS AND METHOD OMEROS CORPORATION (US) 2004-02-05 WO claimed
US-20040023805-A1 Substituted phenyluracils ANDREE ROLAND (DE) 2004-02-05 US claimed
US-6649760-B2 Herbicides BAYER AKTIENGESELLSCHAFT (DE) 2003-11-18 US claimed
US-20020173425-A1 Substituted phenyluracils BAYER AKTIENGESELLSCHAFT (DE) 2002-11-21 US claimed
US-20020156129-A1 Method of treating pruritus and a pharmaceutical composition for the method IKEDA MOHANDO CO., LTD. (JP) 2002-10-24 US claimed
WO-2002069910-A2 USE OF SUBSTANCES THAT PREVENT THAT THE NO SYNTHASE OF WARM-BLOODED ORGANISMS TAKES EFFECT, FOR PRODUCING COSMETIC OR DERMATOLOGICAL PREPARATIONS FOR THE TREATMENT AND/OR THE PROPHYLAXIS OF UNDESIRED SKIN PIGMENTATION BEIERSDORF AG (DE) 2002-09-12 WO claimed
US-20010031727-A1 Therapies using hemoproteins DUKE UNIVERSITY MEDICAL CENTER (US) 2001-10-18 US claimed
EP-1096950-A2 THERAPIES USING HEMOPROTEINS DUKE UNIVERSITY MEDICAL CENTER (US) 2001-05-09 EP claimed
WO-2000002580-A2 THERAPIES USING HEMOPROTEINS DUKE UNIVERSITY MEDICAL CENTER (US) 2000-01-20 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020173425-A1 Substituted phenyluracils DPYD, POP1, G6PD ARG2 1111/4885ARG1 1076/4885GSR 267/4885
US-20040023805-A1 Substituted phenyluracils DPYD, POP1, G6PD ARG2 1111/4885ARG1 1076/4885GSR 267/4885
US-12251449-B2 Synthetic multidomain peptide biomaterials that inhibit inducible nitric oxide synthase STING1, CGAS, GMPS ARG2 53/4885ARG1 5/4885GSR 1070/4885
US-20250276085-A1 SYNTHETIC MULTIDOMAIN PEPTIDE BIOMATERIALS THAT INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE STING1, CGAS, GMPS ARG2 53/4885ARG1 5/4885GSR 1070/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.