Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 7/20 | 0.56 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.56 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.50 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.50 |
| ▸ | CHRNG | P07510 | 1/20 | 0.50 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.50 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.50 |
| ▸ | CHRND | Q07001 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12149734 | 0.88 | CHRNB2 (0.54) | CHRNB2CHRNA4LMNATDP1 | |
| SCHEMBL6326267 | 0.83 | CHRNB2 (0.50) | CHRNB2CHRNA4 | |
| SCHEMBL392062 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL2580295 | 0.82 | CHRNB2 (0.53) | CHRNB2CHRNA4 | |
| Ethane SCHEMBL28825915 | 0.82 | CHRNB2 (0.56) | CHRNB2CHRNA4CHRNA3CHRNA7 | |
| SCHEMBL31742565 | 0.81 | CHRNB2 (0.65) | CHRNB2CHRNA4CHRNA3CHRNA7LMNA | |
| SCHEMBL23745944 | 0.79 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA3CHRNA7LMNA | |
| SCHEMBL14351334 | 0.79 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNA3CHRNA7LMNA | |
| SCHEMBL14351335 | 0.79 | CHRNB2 (0.49) | CHRNB2CHRNA4CHRNA3CHRNA7LMNA | |
| SCHEMBL434891 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
| EP-2086325-A1 | PYRIDINE COMPOUNDS FOR COMBATING PESTS | BASF SE (DE) | 2009-08-12 | — | — | EP | disclosed |
| WO-2008065145-A1 | PYRIDINE COMPOUNDS FOR COMBATING PESTS | BASF SE (DE) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | CHRNB2 169/4885CHRNA4 70/4885CHRNA3 99/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.