Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.35 |
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28140395 | 0.83 | CYP3A4 (0.47) | CYP3A4ALOX15CYP19A1CFTRGOPC | |
| SCHEMBL364562 | 0.80 | CYP3A4 (0.44) | CYP3A4ALOX15CYP19A1CFTRGOPC | |
| SCHEMBL28459231 | 0.71 | SMN1; SMN2 (0.46) | CYP3A4ALOX15SMN1; SMN2CYP2C9GLA | |
| SCHEMBL27789414 | 0.70 | NPC1 (0.33) | ATMNPSR1GAA | |
| SCHEMBL27914390 | 0.69 | KCNE1 (0.33) | CYP3A4ALOX15SMN1; SMN2ATMCYP2C9 | |
| SCHEMBL27866152 | 0.68 | CYP3A4 (0.46) | CYP3A4ALOX15CYP19A1CYP2C9CYP1A2 | |
| SCHEMBL6239972 | 0.68 | CYP19A1 (0.42) | CYP3A4ALOX15CYP19A1CYP2C9IDO1 | |
| SCHEMBL27677963 | 0.67 | CYP3A4 (0.42) | CYP3A4ALOX15CYP19A1CFTRGOPC | |
| SCHEMBL16291560 | 0.67 | CYP3A4 (0.35) | CYP3A4ALOX15ATMCYP2C9GLA | |
| SCHEMBL27885543 | 0.67 | SIGMAR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1542871-A1 | METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA | Creo SRL (CA) | 2005-06-22 | — | — | EP | claimed |
| WO-2004007200-A1 | METHOD FOR MAKING PRINTING PLATE BY INKJET DEPOSITION ON POSITIVE-WORKING MEDIA | CREO SRL (CA) | 2004-01-22 | — | — | WO | claimed |
| US-20180132516-A1 | POSITIVE ALLOSTERIC MODULATORS OF SWEET TASTE | SENSORYGEN INC (US) | 2018-05-17 | — | — | US | disclosed |
| US-20160143878-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2016-05-26 | — | — | US | disclosed |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | JUNTENDO EDUCATIONAL FOUNDATION (JP) | 2015-11-12 | — | — | US | disclosed |
| US-20100048494-A1 | Natural Products from Vinca | RICE UNIVERSITY (US) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160143878-A1 | ANTIBACTERIAL AGENT | MRPL21, Q6ZSR9, NQO2 | CYP3A4 647/4885ALOX15 2774/4885CYP19A1 1340/4885 |
| US-20150322033-A1 | ANTIBACTERIAL AGENT | Q6ZSR9, MRPL21, NQO2 | CYP3A4 734/4885ALOX15 2783/4885CYP19A1 1498/4885 |
| US-20100048494-A1 | Natural Products from Vinca | HIRA, RDX, SLC22A8 | CYP3A4 790/4885ALOX15 4652/4885CYP19A1 227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.