SCHEMBL3221367

SCHEMBL3221367

CC(=O)C(=O)CNc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1Br

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.31
KMT2A Q03164 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GHSR Q92847 1/20 0.31
CA1 P00915 2/20 0.30
CA2 P00918 2/20 0.30
CA9 Q16790 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL388398 0.83 LMNA (0.41) POLBKMT2AL3MBTL1MAPT
SCHEMBL392517 0.78
SCHEMBL15475756 0.78 SMN1; SMN2 (0.31)
SCHEMBL3233252 0.77 ALDH1A1 (0.30) CA1CA2CA9MAPT
SCHEMBL4530063 0.76 CYP1A2 (0.45) L3MBTL1MAPT
SCHEMBL4535465 0.73
SCHEMBL3229602 0.71 ALDH1A1 (0.38) KMT2AMAPT
SCHEMBL389280 0.70 LMNA (0.42) POLBKMT2AL3MBTL1MAPT
SCHEMBL391288 0.70 LMNA (0.41) POLBL3MBTL1MAPT
SCHEMBL7741963 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8465671-B2 Dichroic dye for color filter, composition comprising the same for color filter and color filter array prepared therefrom LG CHEM, LTD. (KR) 2013-06-18 US disclosed
US-20100066950-A1 DICHROIC DYE FOR COLOR FILTER, COMPOSITION COMPRISING THE SAME FOR COLOR FILTER AND COLOR FILTER ARRAY PREPARED THEREFROM EMTIER CO., LTD. (KR) 2010-03-18 US disclosed