SCHEMBL388398

SCHEMBL388398

CCOC(=O)CNc1ccc(-c2nc(C(Cl)(Cl)Cl)nc(C(Cl)(Cl)Cl)n2)cc1Br

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
HPGD P15428 5/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
GAA P10253 6/20 0.38
KDM4E B2RXH2 6/20 0.36
HTT P42858 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
CASP1 P29466 2/20 0.36
ALDH1A1 P00352 8/20 0.36
MAPT P10636 3/20 0.36
HSD17B10 Q99714 2/20 0.36
TP53 P04637 1/20 0.36
MAPK1 P28482 1/20 0.36
CASP7 P55210 1/20 0.36
POLB P06746 1/20 0.36
PPID Q08752 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
HDAC4 P56524 1/20 0.35
HDAC6 Q9UBN7 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL389280 0.88 LMNA (0.42) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL391288 0.87 LMNA (0.41) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL15475756 0.85 SMN1; SMN2 (0.31) SMN1; SMN2
SCHEMBL4530063 0.84 CYP1A2 (0.45) LMNAHPGDSMN1; SMN2KDM4EL3MBTL1
SCHEMBL27938094 0.84 CASP1 (0.47) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL3221367 0.83 POLB (0.31) L3MBTL1MAPTPOLBKMT2A
SCHEMBL388892 0.82 POLB (0.51) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL388857 0.78 ALDH1A1 (0.43) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL327196 0.78 KDM4E (0.34) LMNAHPGDSMN1; SMN2GAAKDM4E
SCHEMBL393007 0.78 POLB (0.43) LMNAHPGDSMN1; SMN2GAAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT FUJIFILM CORPORATION (JP) 2024-01-18 US disclosed
US-10591816-B2 Photosensitive resin composition, color filter, and liquid crystal display element thereof CHI MEI CORPORATION (TW) 2020-03-17 US disclosed
US-9939568-B2 Photosensitive resin composition for color filter and application of the same CHI MEI CORPORATION (TW) 2018-04-10 US disclosed
US-20180004086-A1 NEGATIVE PHOTOSENSITIVE RESIN COMPOSITION, PRODUCTION METHOD OF SPACER, PRODUCTION METHOD OF PROTECTION FILM, AND LIQUID CRYSTAL DISPLAY DEVICE CHI MEI CORPORATION (TW) 2018-01-04 US disclosed
US-9791773-B2 Photosensitive resin composition, color filter and liquid crystal display device CHI MEI CORPORATION (TW) 2017-10-17 US disclosed
US-20170235224-A1 PHOTOSENSITIVE RESIN COMPOSITION, COLOR FILTER, AND LIQUID CRYSTAL DISPLAY ELEMENT THEREOF CHI MEI CORPORATION (TW) 2017-08-17 US disclosed
US-9606436-B2 Photosensitive resin composition and application thereof CHI MEI CORPORATION (TW) 2017-03-28 US disclosed
US-20170052446-A1 PHOTOSENSITIVE RESIN COMPOSITION AND APPLICATION THEREOF CHI MEI CORPORATION (TW) 2017-02-23 US disclosed
US-9557443-B2 Photosensitive resin composition, black matrix, color filter, and liquid crystal display device CHI MEI CORPORATION (TW) 2017-01-31 US disclosed
US-20170003586-A1 PHOTOSENSITIVE RESIN COMPOSITION AND USES THEREOF CHI MEI CORPORATION (TW) 2017-01-05 US disclosed
EP-1348739-A2 Dye-containing curable composition, color filter prepared using the same, and process of preparing color filter FUJI PHOTO FILM CO., LTD. (JP) 2003-10-01 EP disclosed
US-6191184-B1 SUITABLE FOR FORMATION OF LIQUID CRYSTAL DISPLAY (LCD) SPACERS OR PROTECTIVE LAYERS; PHOTOSETTING PROPERTIES ADHESIVENESS TO SUBSTRATES; MECHANICAL CHARACTERISTICS, STORAGE STABILITY SHOW EXCELLENT WORKING FUJI PHOTO FILM CO., LTD. (JP) 2001-02-20 US disclosed
US-6140016-A LIGHT SENSITIVE ELEMENTS AND COLOR FILTERS FUJI PHOTO FILM CO. LTD. (JP) 2000-10-31 US disclosed
US-6100312-A A CURABLE QUATERNARY AMMONIUM ADDITION COPOLYMER WITH A DISPERSED FINE-GRAIN PIGMENT; STORAGE STABILITY; COLOR FILTER USED IN A LIQUID CRYSTAL DISPLAY ELEMENT FUJI PHOTO CO., LTD. (JP) 2000-08-08 US disclosed
US-5998091-A COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0683434-B1 Photo-polymerizable composition, and image forming method and color filter using the composition FUJI PHOTO FILM CO LTD (JP) 1998-12-02 EP disclosed
EP-0683434-A1 Photo-polymerizable composition, and image forming method and color filter using the composition FUJI PHOTO FILM CO., LTD. (JP) 1995-11-22 EP disclosed
EP-0320264-B1 Colour filter MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) 1994-04-27 EP disclosed
US-4934791-A PHOTOSENSITIVE ACRYLATE MONOMER, PIGMENTS, A BINDER AND A PHOTOPOLYMERIZATION INITIATOR MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1990-06-19 US disclosed
EP-0320264-A2 Colour filter MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 1989-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240016965-A1 ULTRAVIOLET-SENSING MEMBER AND ULTRAVIOLET-SENSING KIT KIT, SARS1, UNG LMNA 2337/4885HPGD 3137/4885SMN1; SMN2 4735/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.