Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.41 |
| ▸ | PGR | P06401 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551861 | 0.89 | SMN1; SMN2 (0.44) | NR3C1SMOLMNA | |
| SCHEMBL4552036 | 0.85 | NR3C1 (0.53) | NR3C1SMOARPGR | |
| SCHEMBL4566694 | 0.80 | NR3C1 (0.62) | NR3C1ARPGR | |
| SCHEMBL3215358 | 0.80 | NR3C1 (0.62) | NR3C1ARPGR | |
| SCHEMBL3260372 | 0.76 | NR3C1 (0.49) | NR3C1SMOARPGR | |
| SCHEMBL3203403 | 0.76 | NR3C1 (0.49) | NR3C1SMOARPGR | |
| SCHEMBL4552034 | 0.75 | NR3C1 (0.49) | NR3C1SMOARPGR | |
| SCHEMBL4550490 | 0.72 | NR3C1 (0.46) | NR3C1SMOPGR | |
| SCHEMBL3227153 | 0.72 | SMO (0.53) | NR3C1SMOARPGR | |
| SCHEMBL13493340 | 0.69 | NPY5R (0.50) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-03-11 | — | — | US | disclosed |
| EP-2136634-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124665-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |
| WO-2008124665-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063282-A1 | Glucocorticoid Mimetics, Methods of Making Them, Pharmaceutical Compositions, and Uses Thereof | NR3C1, MC2R, NR3C2 | NR3C1 1/4885SMO 3385/4885AR 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.