Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 19/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 2/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227153 | 0.77 | SMO (0.53) | NR3C1SMOARPGR | |
| SCHEMBL4552036 | 0.76 | NR3C1 (0.53) | NR3C1SMOARPGR | |
| SCHEMBL3848367 | 0.75 | NR3C1 (0.57) | NR3C1PGR | |
| SCHEMBL3221497 | 0.75 | NR3C1 (0.46) | NR3C1SMOARPGR | |
| SCHEMBL4566694 | 0.71 | NR3C1 (0.62) | NR3C1ARPGR | |
| SCHEMBL3215358 | 0.71 | NR3C1 (0.62) | NR3C1ARPGR | |
| SCHEMBL3203403 | 0.70 | NR3C1 (0.49) | NR3C1SMOARPGR | |
| SCHEMBL3260372 | 0.70 | NR3C1 (0.49) | NR3C1SMOARPGR | |
| SCHEMBL3592736 | 0.66 | NR3C1 (1.00) | NR3C1ARPGR | |
| SCHEMBL28268066 | 0.66 | CA2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136634-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | Boehringer Ingelheim International GmbH (DE) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008124665-A1 | GLUCOCORTICOID MIMETICS, METHODS OF MAKING THEM, PHARMACEUTICAL COMPOSITIONS, AND USES THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-10-16 | — | — | WO | disclosed |