SCHEMBL3221824

SCHEMBL3221824

CC(C)C[C@H](NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCCN)NC(=O)CNC(=O)CCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ OPRK1 P41145 7/20 0.56
▸ OPRM1 P35372 7/20 0.56
▸ OPRD1 P41143 5/20 0.55
▸ F2 P00734 1/20 0.54
▸ REN P00797 1/20 0.54
▸ NTSR1 P30989 1/20 0.52
▸ NMUR2 Q9GZQ4 1/20 0.52
▸ NMUR1 Q9HB89 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3866931 0.92 OPRK1 (0.58) OPRK1OPRM1OPRD1F2REN
SCHEMBL3221787 0.90 OPRK1 (0.59) OPRK1OPRM1F2NTSR1NMUR2
SCHEMBL3221767 0.90 OPRK1 (0.59) OPRK1OPRM1F2NTSR1NMUR2
SCHEMBL3204393 0.88 OPRK1 (0.59) OPRK1OPRM1OPRD1F2REN
SCHEMBL3204375 0.88 OPRK1 (0.59) OPRK1OPRM1OPRD1F2REN
SCHEMBL8341612 0.85 OPRD1 (0.55) OPRK1OPRM1OPRD1F2NTSR1
SCHEMBL8341607 0.85 OPRD1 (0.55) OPRK1OPRM1OPRD1F2NTSR1
SCHEMBL30899147 0.84 NMUR2 (0.59) OPRM1OPRD1F2NMUR2NMUR1
SCHEMBL29679546 0.84 OPRD1 (0.60) OPRM1OPRD1F2
SCHEMBL31575698 0.83 F2 (0.56) OPRK1OPRM1OPRD1F2NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8962697-B2 Bioreponsive polymers INTERFACE BIOLOGICS INC. (CA) 2015-02-24 — — US disclosed
US-20100041771-A1 Bioreponsive Polymers INTERFACE BIOLOGICS, INC. 2010-02-18 — — US disclosed
EP-2040758-A2 BIORESPONSIVE POLYMERS Interface Biologics Inc. (CA) 2009-04-01 — — EP disclosed
WO-2008053362-A2 BIORESPONSIVE POLYMERS INTERFACE BIOLOGICS, INC. (CA) 2008-05-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100041771-A1 Bioreponsive Polymers PEPD, PREP, DNPEP OPRK1 2985/4885OPRM1 3402/4885OPRD1 3114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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