Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 5/20 | 0.55 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.55 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.53 |
| ▸ | MC4R | P32245 | 1/20 | 0.53 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.52 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.52 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8341612 | 1.00 | OPRD1 (0.55) | OPRD1KEAP1OPRK1NMUR2OPRM1 | |
| SCHEMBL31040682 | 0.89 | OPRD1 (0.58) | OPRD1OPRK1OPRM1 | |
| SCHEMBL30512651 | 0.88 | NTSR1 (0.55) | OPRD1KEAP1OPRK1OPRM1NTSR2 | |
| Thymoctonan SCHEMBL15532000 | 0.86 | REN (0.52) | OPRD1KEAP1OPRK1OPRM1NTSR2 | |
| Thymoctonan SCHEMBL1230532 | 0.86 | REN (0.52) | OPRD1KEAP1OPRK1OPRM1NTSR2 | |
| SCHEMBL30261995 | 0.86 | OPRD1 (0.61) | OPRD1OPRK1NMUR2OPRM1NMUR1 | |
| SCHEMBL30432935 | 0.85 | NMUR2 (0.61) | OPRK1NMUR2OPRM1MC4RNMUR1 | |
| SCHEMBL29440484 | 0.85 | KEAP1 (0.60) | OPRD1KEAP1NMUR2OPRM1NMUR1 | |
| SCHEMBL3221824 | 0.85 | OPRK1 (0.56) | OPRD1OPRK1NMUR2OPRM1NTSR1 | |
| SCHEMBL29679774 | 0.84 | OPRD1 (0.57) | OPRD1KEAP1OPRK1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5874405-A | PROVIDES FOR PEPTIDES AND METHODS OF USING PEPTIDES TO BLOCK OR INHIBIT A PATHOGENIC AUTOIMMUNE RESPONSE TO CENTRAL NERVOUS SYSTEM COMPONENTS; USEFUL DIAGNOSTICALLY TO SCREEN PEPTIDE OR PEPTIDE ANALOGS THAT CAN INHIBIT PATHOGENIC IMMUNE RESPONSE | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 1999-02-23 | — | — | US | claimed |
| WO-1996018646-A2 | HEAT SHOCK PROTEIN PEPTIDES AND METHODS FOR MODULATING AUTOIMMUNE CENTRAL NERVOUS SYSTEM DISEASE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-06-20 | — | — | WO | claimed |
| US-5958416-A | Heat shock protein peptides and methods for modulating autoimmune central nervous system disease | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1996018646-A2 | HEAT SHOCK PROTEIN PEPTIDES AND METHODS FOR MODULATING AUTOIMMUNE CENTRAL NERVOUS SYSTEM DISEASE | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 1996-06-20 | — | — | WO | disclosed |