Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 16/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.34 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3203305 | 0.90 | AQP1 (0.40) | AQP1ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL3195046 | 0.85 | ALDH1A1 (0.37) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL3194965 | 0.84 | AQP1 (0.46) | AQP1TSHRRORC | |
| SCHEMBL4224582 | 0.79 | AQP1 (0.59) | AQP1ALDH1A1CYP3A4CYP2D6TSHR | |
| SCHEMBL13487006 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL13487008 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL13487000 | 0.79 | ALDH1A1 (0.42) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL3264386 | 0.78 | POLB (0.39) | AQP1ALDH1A1CYP3A4TSHRCYP2C9 | |
| SCHEMBL7911444 | 0.78 | ALDH1A1 (0.38) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 | |
| SCHEMBL6975655 | 0.77 | MAPT (0.45) | ALDH1A1CYP3A4CYP2D6TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | WYETH | 2010-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100035871-A1 | BENZOXAZINE DERIVATIVES AND USES THEREOF | HTR2C, HTR5A, NPY1R | AQP1 2125/4885ALDH1A1 1164/4885CYP3A4 298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.