Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.52 |
| ▸ | PNMT | P11086 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30377 | 0.90 | IDO1 (0.61) | IDO1PNMTMAOBMAOATAAR1 | |
| Phosphine SCHEMBL20719631 | 0.88 | IDO1 (0.59) | IDO1PNMTMAOBMAOATAAR1 | |
| SCHEMBL3220315 | 0.78 | SMN1; SMN2 (0.42) | TAAR1KMT2AMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL3207748 | 0.77 | L3MBTL1 (0.43) | MAPTL3MBTL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL3221093 | 0.76 | IDO1 (0.56) | IDO1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL28089473 | 0.74 | IDO1 (0.53) | IDO1PNMTMAOBMAOATAAR1 | |
| SCHEMBL15834275 | 0.74 | IDO1 (0.41) | IDO1PNMTMEN1KMT2A | |
| SCHEMBL1145314 | 0.74 | IDO1 (0.64) | IDO1PNMTTAAR1MEN1KMT2A | |
| SCHEMBL648491 | 0.73 | IDO1 (0.44) | IDO1TAAR1MEN1KMT2AMAPT | |
| SCHEMBL9419151 | 0.73 | IDO1 (0.52) | IDO1PNMTMAOBMAOATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8273885-B2 | Fluoroboron compound having aromatic ring or salt thereof, and method for producing compound having cyclic ether-fused aromatic ring using the same | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2012-09-25 | — | — | US | disclosed |
| US-20100056788-A1 | FLUOROBORON COMPOUND HAVING AROMATIC RING OR SALT THEREOF, AND METHOD FOR PRODUCING COMPOUND HAVING CYCLIC ETHER-FUSED AROMATIC RING USING THE SAME | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2010-03-04 | — | — | US | disclosed |
| EP-2062901-A1 | FLUOROBORON COMPOUND HAVING AROMATIC RING OR SALT THEREOF, AND PROCESS FOR PRODUCTION OF COMPOUND HAVING CYCLIC ETHER-FUSED AROMATIC RING BY USING THE SAME | Eisai R&D Management Co., Ltd. (JP) | 2009-05-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056788-A1 | FLUOROBORON COMPOUND HAVING AROMATIC RING OR SALT THEREOF, AND METHOD FOR PRODUCING COMPOUND HAVING CYCLIC ETHER-FUSED AROMATIC RING USING THE SAME | FLI1, AFF1, MLLT3 | IDO1 3658/4885PNMT 1652/4885MAOB 363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.