SCHEMBL3222569

SCHEMBL3222569

CC(C)c1ccccc1-c1[c]cccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.40
GABRB2 P47870 2/20 0.40
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
DPP4 P27487 2/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
FAAH O00519 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
LMNA P02545 1/20 0.37
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
HPGD P15428 1/20 0.37
TSHR P16473 1/20 0.37
GABRB1 P18505 1/20 0.37
PTGS1 P23219 1/20 0.37
SLC6A2 P23975 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11293458 0.86 GABRA1 (0.32) GABRA1GABRB2CA1CA2CA12
SCHEMBL8122110 0.85 DPP4 (0.37) GABRA1GABRB2CA1CA2CA12
SCHEMBL9690677 0.83 TYR (0.38) GABRA1GABRB2DPP4NR1H2NR1H3
SCHEMBL2761711 0.79 MEN1 (0.32) LMNABLML3MBTL1PPARG
SCHEMBL3223847 0.79 GABRA1 (0.41) GABRA1GABRB2CA1CA2DPP4
SCHEMBL8855149 0.77 MEN1 (0.35) LMNATSHRBLML3MBTL1PPARG
SCHEMBL322239 0.77 MEN1 (0.35) LMNATSHRBLML3MBTL1PPARG
SCHEMBL167078 0.77 GABRA1 (0.55) GABRA1GABRB2CA1CA2CA12
SCHEMBL29414063 0.77 GABRA1 (0.55) GABRA1GABRB2CA1CA2CA12
SCHEMBL9712242 0.76 GABRA1 (0.38) GABRA1GABRB2CA1CA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1581341-A1 TRIMERISATION OF OLEFINS Sasol Technology (Pty) Ltd (ZA) 2005-10-05 EP claimed
WO-2004056477-A1 TRIMERISATION OF OLEFINS SASOL TECHNOLOGY (PTY) LIMITED (ZA) 2004-07-08 WO claimed
US-5159074-A AMINOMETHANEPHOSPHONIC ACID ARYL ESTERS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE BAYER AKTIENGESELLSCHAFT (DE) 1992-10-27 US claimed
EP-0248404-B1 ETHYLENE COPOLYMERS WITH ENHANCED FIRE RESISTANT PROPERTIES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-12-04 EP claimed
US-4849135-A ALUMINA, CALCIUM CARBONATE, CALCIUM-MAGNESIUM CARBONATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-18 US claimed
US-4532085-A Extracting esters from distillation residues with hydrocarbon solvent STAUFFER CHEMICAL COMPANY (US) 1985-07-30 US claimed
US-3931367-A Color improvement of phosphate esters STAUFFER CHEMICAL COMPANY (US) 1976-01-06 US claimed
EP-4291592-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP America Inc. (US) 2023-12-20 EP disclosed
WO-2022173532-A1 FLAME LAMINATION ADDITIVE FOR POLYURETHANE FOAM ICL-IP AMERICA INC. (US) 2022-08-18 WO disclosed
EP-3606971-B1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2022-01-12 EP disclosed
US-20200181359-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL IP AMERICA INC (US) 2020-06-11 US disclosed
US-10597511-B2 Reactive flame retardant blends for flexible polyurethane foam ICL-IP AMERICA INC. (US) 2020-03-24 US disclosed
EP-3606971-A1 REACTIVE FLAME RETARDANT BLENDS FOR FLEXIBLE POLYURETHANE FOAM ICL-IP America Inc. (US) 2020-02-12 EP disclosed
US-4849135-A ALUMINA, CALCIUM CARBONATE, CALCIUM-MAGNESIUM CARBONATE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1989-07-18 US disclosed
EP-0248404-A2 Ethylene copolymers with enhanced fire resistant properties E.I. DU PONT DE NEMOURS AND COMPANY (US) 1987-12-09 EP disclosed
EP-0005053-B1 FLAME-RETARDANT ORGANIC PHOSPHATES, THEIR PRODUCTION, AND COMPOSITIONS CONTAINING THEM FMC Corporation (US) 1983-05-25 EP disclosed
US-4246169-A Flammable plastics containing a flame retardant amount of polyarylphosphates and the polyarylphosphates FMC CORPORATION (US) 1981-01-20 US disclosed
US-4212832-A REACTING PHOSPHONIC OR PHOSPHORIC ACID ARYL ESTER WITH FORMALDEHYDE AND SULFURIC ACID; FLAME-PROOFING AGENT BAYER AKTIENGESELLSCHAFT (DE) 1980-07-15 US disclosed
EP-0005053-A2 Flame-retardant organic phosphates, their production, and compositions containing them FMC Corporation (US) 1979-10-31 EP disclosed
US-4163731-A HYDRAULIC FLUIDS CIBA-GEIGY AG (CH) 1979-08-07 US disclosed