Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | FAAH | O00519 | 1/20 | 0.30 |
| ▸ | MGLL | Q99685 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222569 | 0.86 | GABRA1 (0.40) | GABRA1GABRB2DPP4NR1H2NR1H3 | |
| SCHEMBL9690677 | 0.79 | TYR (0.38) | GABRA1GABRB2DPP4NR1H2NR1H3 | |
| SCHEMBL8122110 | 0.76 | DPP4 (0.37) | GABRA1GABRB2DPP4NR1H2NR1H3 | |
| SCHEMBL2761711 | 0.75 | MEN1 (0.32) | — | |
| SCHEMBL322239 | 0.73 | MEN1 (0.35) | — | |
| SCHEMBL8855149 | 0.73 | MEN1 (0.35) | — | |
| SCHEMBL3223847 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2DPP4NR1H2NR1H3 | |
| SCHEMBL981109 | 0.70 | TSHR (0.39) | CA12CA1CA2CA9 | |
| SCHEMBL1004314 | 0.70 | CA12 (0.42) | DPP4CA12CA1CA2CA9 | |
| SCHEMBL707769 | 0.70 | MEN1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002821-B1 | CYCLIC PHOSPHITES AND ORGANIC MATERIAL STABILIZED BY THEM | CIBA-GEIGY AG (CH) | 1982-06-23 | — | — | EP | disclosed |
| US-4196117-A | Alkylated 1,1'-biphenyl-2,2'-diyl phosphites and stabilized compositions | CIBA-GEIGY CORPORATION (US) | 1980-04-01 | — | — | US | disclosed |
| EP-0002821-A1 | Cyclic phosphites and organic material stabilized by them | CIBA-GEIGY AG (CH) | 1979-07-11 | — | — | EP | disclosed |