SCHEMBL3222745

SCHEMBL3222745

O=C(O/N=C/c1ccccc1)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PLA2G7 Q13093 7/20 1.00
MIF P14174 1/20 0.81
MAPT P10636 5/20 0.54
KDM4E B2RXH2 2/20 0.53
ALDH1A1 P00352 2/20 0.53
GAA P10253 1/20 0.53
RAB9A P51151 4/20 0.51
KMT2A Q03164 2/20 0.51
CA1 P00915 2/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.49
CA9 Q16790 1/20 0.49
F2 P00734 1/20 0.48
LMNA P02545 1/20 0.48
NPC1 O15118 3/20 0.48
FAAH O00519 1/20 0.48
NFKB1 P19838 1/20 0.46
NFKB2 Q00653 1/20 0.46
RELA Q04206 1/20 0.46
MEN1 O00255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3222751 1.00 PLA2G7 (1.00) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL13930605 0.93 PLA2G7 (0.87) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL13595497 0.90 MIF (1.00) PLA2G7MIFMAPTKDM4EALDH1A1
Diacetamide SCHEMBL3221443 0.89 PLA2G7 (0.79) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL3225274 0.88 PLA2G7 (1.00) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL3225285 0.88 PLA2G7 (1.00) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL4259699 0.85 PLA2G7 (0.73) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL4259696 0.85 PLA2G7 (0.73) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL27854906 0.84 PLA2G7 (0.71) PLA2G7MIFMAPTKDM4EALDH1A1
SCHEMBL3233962 0.83 PLA2G7 (0.75) PLA2G7MIFMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060106017-A1 NOVEL O-ACYLOXIME DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2006-05-18 US claimed
US-9488911-B2 Photosensitive composition, photocurable composition, chemical amplification resist composition, resist film, pattern forming method, method of manufacturing electronic device and electronic device FUJIFILM CORPORATION (JP) 2016-11-08 US disclosed
US-9488911-B2 Photosensitive composition, photocurable composition, chemical amplification resist composition, resist film, pattern forming method, method of manufacturing electronic device and electronic device FUJIFILM CORPORATION (JP) 2016-11-08 US disclosed
US-20150362836-A1 PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, CHEMICAL AMPLIFICATION RESIST COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, METHOD OF MANUFACTURING ELECTRONIC DEVICE AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-20150362836-A1 PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, CHEMICAL AMPLIFICATION RESIST COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, METHOD OF MANUFACTURING ELECTRONIC DEVICE AND ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2015-12-17 US disclosed
US-8822109-B2 Colored curable composition, color filter, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8822109-B2 Colored curable composition, color filter, and solid image pickup element FUJIFILM CORPORATION (JP) 2014-09-02 US disclosed
US-8507175-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-08-13 US disclosed
US-8507175-B2 Patterning process and resist composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2013-08-13 US disclosed
US-8440374-B2 Colored curable composition, color filter and method of producing the same, and solid-state imaging device FUJIFILM CORPORATION (JP) 2013-05-14 US disclosed
US-7338748-B2 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION (JP) 2008-03-04 US disclosed
US-7300740-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-7300740-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070202439-A1 Polymerizable composition and planographic printing plate precursor FUJIFILM CORPORATION 2007-08-30 US disclosed
US-20070072116-A1 comprising hydrophilic support, undercoat layer and laser-sensitive photopolymerizable layer, wherein undercoat layer contains copolymer containing a repeating unit having at least one ethylenically unsaturated bond and repeating unit having functional group capable of interacting with surface of support FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-20070072116-A1 comprising hydrophilic support, undercoat layer and laser-sensitive photopolymerizable layer, wherein undercoat layer contains copolymer containing a repeating unit having at least one ethylenically unsaturated bond and repeating unit having functional group capable of interacting with surface of support FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
US-7183038-B2 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed
US-7183038-B2 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2007-02-27 US disclosed
US-20060106017-A1 NOVEL O-ACYLOXIME DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) 2006-05-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150362836-A1 PHOTOSENSITIVE COMPOSITION, PHOTOCURABLE COMPOSITION, CHEMICAL AMPLIFICATION RESIST COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, METHOD OF MANUFACTURING ELECTRONIC DEVICE AND ELECTRONIC DEVICE POLQ, POLR1A, POLI PLA2G7 1237/4885MIF 4600/4885MAPT 302/4885
US-20060106017-A1 NOVEL O-ACYLOXIME DERIVATIVES, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME FOR PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASE PLA2G7, ALOX5AP, LPL PLA2G7 1/4885MIF 2019/4885MAPT 4854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.