Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G7 | Q13093 | 7/20 | 0.73 |
| ▸ | MIF | P14174 | 2/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4259696 | 1.00 | PLA2G7 (0.73) | PLA2G7MIFFFAR1MAPTKDM4E | |
| SCHEMBL3222745 | 0.85 | PLA2G7 (1.00) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL3222751 | 0.85 | PLA2G7 (1.00) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL13930605 | 0.83 | PLA2G7 (0.87) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL13595497 | 0.83 | MIF (1.00) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL3225285 | 0.81 | PLA2G7 (1.00) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL3225274 | 0.81 | PLA2G7 (1.00) | PLA2G7MIFMAPTKDM4EGAA | |
| SCHEMBL4259708 | 0.78 | NPC1 (0.71) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL4259706 | 0.78 | NPC1 (0.71) | MAPTALDH1A1KMT2ARAB9ANPC1 | |
| SCHEMBL27854906 | 0.78 | PLA2G7 (0.71) | PLA2G7MIFMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7488721-B2 | Real time methylumbelliferone-based assay | MCMASTER UNIVERSITY (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20060008862-A1 | Real time methylumbelliferone-based assay | THE HOSPITAL FOR SICK CHILDREN | 2006-01-12 | — | — | US | disclosed |