Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 5/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
| ▸ | USP2 | O75604 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | CASP3 | P42574 | 1/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15151635 | 0.87 | RAB9A (0.71) | RAB9AALDH1A1HPGDLMNAGAA | |
| SCHEMBL15151500 | 0.86 | RAB9A (0.66) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL15151410 | 0.86 | RAB9A (0.66) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL15151541 | 0.86 | RAB9A (0.66) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL15151516 | 0.85 | RAB9A (0.64) | RAB9AALDH1A1HPGDLMNAGAA | |
| SCHEMBL15151643 | 0.85 | HPGD (0.69) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL15151505 | 0.84 | RAB9A (0.80) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL257220 | 0.84 | RAB9A (0.79) | RAB9AALDH1A1HPGDLMNAGAA | |
| SCHEMBL15151511 | 0.84 | RAB9A (0.63) | RAB9AALDH1A1HPGDLMNAHTT | |
| SCHEMBL15151533 | 0.84 | RAB9A (0.63) | RAB9AALDH1A1HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2808324-A1 | PYRROLE COMPOUND | Kabushiki Kaisha Yakult Honsha (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
| US-20140343017-A1 | PYRROLE COMPOUND | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2014-11-20 | — | — | US | disclosed |
| WO-2013111831-A1 | PYRROLE COMPOUND | 株式会社ヤクルト本社 (JP) | 2013-08-01 | — | — | WO | disclosed |
| WO-2010013011-A1 | P53 TUMOR SUPPRESSOR PROTEIN ACTIVATING | UNIVERSITY COURT OF THE UNIVERSITY OF DUNDEE (GB) | 2010-02-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140343017-A1 | PYRROLE COMPOUND | TUBB3, TUBB1, TUBB | RAB9A 781/4885ALDH1A1 2354/4885HPGD 3780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.