Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.66 |
| ▸ | HTR1A | P08908 | 12/20 | 0.66 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.66 |
| ▸ | HRH1 | P35367 | 3/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363791 | 0.88 | HTR1A (0.58) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| SCHEMBL3080032 | 0.80 | SLC6A2 (0.57) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| SCHEMBL2299492 | 0.80 | SLC6A2 (0.64) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| SCHEMBL82955 | 0.79 | HRH1 (0.62) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| Hydrochloric Acid SCHEMBL4095144 | 0.79 | SLC6A2 (0.56) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| Hydrochloric Acid SCHEMBL69459 | 0.78 | HRH1 (0.60) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| SCHEMBL22278138 | 0.78 | SLC6A2 (0.62) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 | |
| SCHEMBL18367733 | 0.77 | SLC6A2 (0.47) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| SCHEMBL31053713 | 0.77 | SLC6A2 (0.47) | SLC6A2HTR1ASLC6A4SLC6A3 | |
| SCHEMBL29003883 | 0.77 | SLC6A2 (0.71) | SLC6A2HTR1ASLC6A4HRH1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4674416-A1 | PROTEIN AGGREGATE DECOMPOSITION PROMOTING COMPOSITION AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES ASSOCIATED WITH PROTEIN AGGREGATE FORMATION | NAGASAKI UNIVERSITY (JP) | 2026-01-07 | — | — | EP | disclosed |
| WO-2024181431-A1 | PROTEIN AGGREGATE DECOMPOSITION PROMOTING COMPOSITION AND PHARMACEUTICAL COMPOSITION FOR PREVENTION OR TREATMENT OF NEURODEGENERATIVE DISEASES ASSOCIATED WITH PROTEIN AGGREGATE FORMATION | 国立大学法人 長崎大学 | 2024-09-06 | — | — | WO | disclosed |
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | XIANG JASON SHAOYUN | 2010-02-04 | — | — | US | disclosed |
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | XIANG JASON SHAOYUN | 2010-02-04 | — | — | US | disclosed |
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | XIANG JASON SHAOYUN | 2010-02-04 | — | — | US | disclosed |
| US-7632838-B2 | 11-beta HSD1 inhibitors | WYETH (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632838-B2 | 11-beta HSD1 inhibitors | WYETH (US) | 2009-12-15 | — | — | US | disclosed |
| US-7632838-B2 | 11-beta HSD1 inhibitors | WYETH (US) | 2009-12-15 | — | — | US | disclosed |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | WYETH (US) | 2007-09-20 | — | — | US | disclosed |
| WO-2007092435-A2 | 11-BETA HSD1 INHIBITORS | WYETH (US) | 2007-08-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029648-A1 | 11-Beta HSD1 Inhibitors | HSD11B1, HSD3B1, HSD11B2 | SLC6A2 2676/4885HTR1A 484/4885SLC6A4 1538/4885 |
| US-20070219198-A1 | 11-Beta HSD 1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | SLC6A2 1873/4885HTR1A 264/4885SLC6A4 889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.