Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.31 |
| ▸ | CTRC | Q99895 | 2/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10406083 | 0.91 | ALDH1A1 (0.35) | MEN1ALDH1A1KMT2AGAAHPGD | |
| SCHEMBL10406473 | 0.81 | FAAH (0.32) | — | |
| SCHEMBL15480919 | 0.80 | — | — | |
| SCHEMBL10406774 | 0.75 | — | — | |
| SCHEMBL10406776 | 0.75 | — | — | |
| SCHEMBL16053721 | 0.74 | — | — | |
| SCHEMBL4099577 | 0.74 | — | — | |
| SCHEMBL4724968 | 0.74 | — | — | |
| SCHEMBL4099579 | 0.74 | — | — | |
| SCHEMBL2886239 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-8809373-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2014-08-19 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-05-16 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8389534-B2 | Pyrimidine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION (US) | 2013-03-05 | — | — | US | disclosed |
| US-8349876-B2 | Pyridine non-classical cannabinoid compounds and related methods of use | THE UNIVERSITY OF TENNESEE RESEARCH FOUNDATION (US) | 2013-01-08 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | THE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2010-03-18 | — | — | US | disclosed |
| US-4921994-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4831059-A | ANTIEMETICS; DIARRHEA; CENTRAL NERVOUS SYSTEM | PFIZER INC. (US) | 1989-05-16 | — | — | US | disclosed |
| EP-0048572-B1 | SUBSTITUTED 2-HYDROXYPHENYL CYCLOALKANES AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1987-07-15 | — | — | EP | disclosed |
| US-4391827-A | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor | PFIZER INC. (US) | 1983-07-05 | — | — | US | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| EP-0048572-A2 | Substituted 2-hydroxyphenyl cycloalkanes and pharmaceutical compositions thereof | PFIZER INC. (US) | 1982-03-31 | — | — | EP | disclosed |
| US-4306097-A | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123304-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | MEN1 4243/4885ALDH1A1 2138/4885KMT2A 1920/4885 |
| US-20100069440-A1 | PYRIDINE NON-CLASSICAL CANNABINOID COMPOUNDS AND RELATED METHODS OF USE | CNR1, CNR2, NPY1R | MEN1 4243/4885ALDH1A1 2138/4885KMT2A 1920/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.