Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222910 | 0.81 | MEN1 (0.33) | — | |
| SCHEMBL13418580 | 0.76 | NLRP3 (0.36) | — | |
| SCHEMBL4817247 | 0.76 | NFKB1 (0.33) | — | |
| SCHEMBL10406083 | 0.73 | ALDH1A1 (0.35) | — | |
| SCHEMBL10738105 | 0.71 | FOLH1 (0.37) | — | |
| SCHEMBL4277023 | 0.71 | — | — | |
| SCHEMBL2886239 | 0.71 | — | — | |
| SCHEMBL21259533 | 0.71 | — | — | |
| SCHEMBL4724968 | 0.71 | — | — | |
| SCHEMBL4099577 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4921994-A | ANALGESICS, ANTIEMETICS | PFIZER INC. (US) | 1990-05-01 | — | — | US | disclosed |
| US-4831059-A | ANTIEMETICS; DIARRHEA; CENTRAL NERVOUS SYSTEM | PFIZER INC. (US) | 1989-05-16 | — | — | US | disclosed |
| US-4391827-A | 3-(2-Hydroxy-4-(substituted)phenyl)-cycloalkanone and cycloalkanol analgesic agents and intermediates therefor | PFIZER INC. (US) | 1983-07-05 | — | — | US | disclosed |
| US-4371720-A | ANTIDIARRHEALS, ANTIEMETICS | PFIZER INC. (US) | 1983-02-01 | — | — | US | disclosed |
| US-4306097-A | 3-[2-Hydroxy-4-(substituted)phenyl]-cycloalkanol analgesic agents | PFIZER INC. (US) | 1981-12-15 | — | — | US | disclosed |