Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21557913 | 0.90 | LMNA (0.44) | SMN1; SMN2RAB9AKEAP1NFE2L2MAPT | |
| SCHEMBL3223036 | 0.86 | RAB9A (0.38) | SMN1; SMN2FFAR4RAB9AKEAP1NFE2L2 | |
| SCHEMBL21551795 | 0.85 | MAPT (0.42) | SMN1; SMN2RAB9AKEAP1NFE2L2MAPT | |
| SCHEMBL2174329 | 0.83 | FFAR4 (0.36) | SMN1; SMN2FFAR4RAB9AKEAP1NFE2L2 | |
| SCHEMBL20140068 | 0.83 | HTR2A (0.42) | SMN1; SMN2FFAR4RAB9AKEAP1NFE2L2 | |
| SCHEMBL23700114 | 0.81 | MAOB (0.46) | SMN1; SMN2RAB9AMAPTHTR2AHTR2C | |
| SCHEMBL21697595 | 0.80 | SMN1; SMN2 (0.37) | SMN1; SMN2FFAR4RAB9AMAPTMAPK1 | |
| SCHEMBL1539311 | 0.80 | LIPE (0.45) | MAPTMAPK1TDP1L3MBTL1RXRA | |
| SCHEMBL3215337 | 0.77 | MAPT (0.42) | SMN1; SMN2FFAR4RAB9AMAPTMAPK1 | |
| SCHEMBL20741981 | 0.76 | TDP1 (0.44) | SMN1; SMN2FFAR4RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2103607-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2009-09-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069460-A1 | 1-PHENYL 1-THIO-D-GLUCITOL DERIVATIVE | SLC5A1, SLC5A2, SLC2A1 | SMN1; SMN2 4236/4885FFAR4 1498/4885RAB9A 3641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.