Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | ERN1 | O75460 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959740 | 0.81 | TDP1 (0.45) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13982690 | 0.79 | HPGD (0.47) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16956383 | 0.79 | TDP1 (0.42) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL10724399 | 0.78 | TDP1 (0.45) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13982728 | 0.78 | TDP1 (0.45) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL13983226 | 0.78 | TSHR (0.58) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16951398 | 0.74 | ERN1 (0.47) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL9193204 | 0.74 | ALDH1A1 (0.68) | TDP1GPR35ALDH1A1TSHRS100A4 | |
| SCHEMBL1507653 | 0.74 | TDP1 (0.44) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 | |
| SCHEMBL16953606 | 0.74 | TSHR (0.46) | TDP1GPR35ALDH1A1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | BASF SE (DE) | 2010-03-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069244-A1 | Pyridine Compounds for Combating Pests | CHRM1, PRDX1, CHRM2 | TDP1 1863/4885GPR35 1206/4885ALDH1A1 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.