SCHEMBL3225115

SCHEMBL3225115

O=C(c1ccccc1)c1ccc(-c2cc[nH]n2)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
RAB9A P51151 3/20 0.50
LMNA P02545 1/20 0.50
MAPT P10636 1/20 0.50
ALDH1A1 P00352 1/20 0.48
SRD5A2 P31213 1/20 0.47
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
CA9 Q16790 1/20 0.44
CA14 Q9ULX7 1/20 0.44
GAA P10253 1/20 0.44
ELANE P08246 2/20 0.43
ATM Q13315 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MAPK13 O15264 1/20 0.42
MAPK12 P53778 1/20 0.42
MAPK11 Q15759 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzophenone SCHEMBL17224646 0.95 ALDH1A1 (0.50) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL17303477 0.93 RXFP1 (0.44) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL1111577 0.84 KDM4E (0.47) RAB9AALDH1A1SRD5A2GAANPC1
SCHEMBL28005164 0.83 IDO1 (0.35) MEN1KMT2ARAB9ALMNAMAPT
Urea SCHEMBL27659773 0.80 TP53 (0.44) MEN1KMT2ALMNAGAAMAPK14
SCHEMBL16800868 0.79 CYP1A2 (0.45) MEN1KMT2ARAB9ALMNAMAPT
SCHEMBL9438 0.79 CYP1A2 (0.48) MEN1KMT2ARAB9AMAPTALDH1A1
SCHEMBL4789775 0.79 ALDH1A1 (0.36) RAB9ALMNAMAPTALDH1A1CA12
SCHEMBL10242672 0.79 XDH (0.49) KMT2ARAB9ALMNAMAPTGAA
Hydrochloric Acid SCHEMBL31747485 0.77 MAPK1 (0.47) KMT2AALDH1A1CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10189987-B2 Pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2019-01-29 US disclosed
EP-3064546-B1 PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2018-08-29 EP disclosed
US-9932460-B2 Rubber composition and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2018-04-03 US disclosed
CN-103450515-B Rubber compound used for studless tire and studless tire 住友橡胶工业株式会社 2017-05-24 CN disclosed
US-20160264772-A1 PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2016-09-15 US disclosed
EP-2674457-B1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER IND (JP) 2016-09-14 EP disclosed
EP-3064546-A1 PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2016-09-07 EP disclosed
CN-103443189-B Rubber composition and pneumatic tire 住友橡胶工业株式会社 2016-09-07 CN disclosed
CN-104334629-B Rubber composition for tire tread and pneumatic tire 住友橡胶工业株式会社 2016-08-24 CN disclosed
CN-105722909-A Pneumatic tire 住友橡胶工业株式会社 2016-06-29 CN disclosed
EP-2597118-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE Sumitomo Rubber Industries, Ltd. (JP) 2013-05-29 EP disclosed
US-20130090409-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2013-04-11 US disclosed
CN-103003348-A Rubber composition and pneumatic tire SUMITOMO RUBBER IND 2013-03-27 CN disclosed
US-8299167-B2 Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-30 US disclosed
US-20120149806-A1 RUBBER COMPOSITION AND PNEUMATIC TIRE SUMITOMO RUBBER INDUSTRIES, LTD. 2012-06-14 US disclosed
EP-2463310-A1 Rubber composition and pneumatic tire Sumitomo Rubber Industries, Ltd. (JP) 2012-06-13 EP disclosed
US-20100056712-A1 CONJUGATED DIENE POLYMER, CONJUGATED DIENE POLYMER COMPOSITION, AND METHOD FOR PRODUCING CONJUGATED DIENE POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-04 US disclosed
CN-101659732-A Conjugated diene polymer, conjugated diene polymer composition, and method for producing conjugated diene polymer SUMITOMO CHEMICAL CO 2010-03-03 CN disclosed
US-7339005-B2 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2008-03-04 US disclosed
US-20040152845-A1 Process for producing modified diene polymer rubber SUMITOMO CHEMICAL COMPANY, LIMITED 2004-08-05 US disclosed