Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 11/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 8/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 6/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 6/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 6/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 6/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 6/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 6/20 | 0.51 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10439757 | 0.89 | MEN1 (0.52) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| Hydrochloric Acid SCHEMBL11409811 | 0.87 | MEN1 (0.51) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL19997327 | 0.86 | HDAC1 (0.60) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL8015974 | 0.86 | HDAC1 (0.60) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL8140115 | 0.86 | CYP1A2 (0.59) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL28929263 | 0.82 | NPC1 (0.62) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL10602228 | 0.82 | HDAC1 (0.49) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL10793524 | 0.82 | LTA4H (0.49) | HDAC1HDAC3HDAC2HDAC8HDAC4 | |
| SCHEMBL9731103 | 0.80 | PLAU (0.58) | HDAC1MEN1KMT2AHDAC3HDAC2 | |
| SCHEMBL8010136 | 0.79 | NR1H4 (0.59) | HDAC1MEN1KMT2AHDAC3HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216802-B2 | Detection medium for gram negative bacteria | BIOMERIEUX (FR) | 2012-07-10 | — | — | US | disclosed |
| US-20100062466-A1 | MEDIUM FOR THE DETECTION AND/OR IDENTIFICATION OF BACTERIA | BIOMERIEUX (FR) | 2010-03-11 | — | — | US | disclosed |
| EP-1235927-B1 | NOVEL ENZYMATIC SUBSTRATES FOR DETECTING PSEUDOMONAS AERUGINOSA | BIOMERIEUX SA (FR) | 2006-03-08 | — | — | EP | disclosed |
| EP-1621530-A1 | Methods, compositions et enzyme substrates for the detection of Pseudomonas Aeruginosa | BIOMERIEUX SA (FR) | 2006-02-01 | — | — | EP | disclosed |
| US-6905841-B2 | Enzymatic substrates for detecting Pseudomonas aeruginas | BIOMERIEUX S.A. (FR) | 2005-06-14 | — | — | US | disclosed |
| US-20030044877-A1 | Novel enzymatic substrates for detecting pseudomonas aeruginosa, compositions containing same and method for detecting said species | BIOMERIEUX S.A. (FR) | 2003-03-06 | — | — | US | disclosed |
| EP-1235927-A2 | NOVEL ENZYMATIC SUBSTRATES FOR DETECTING PSEUDOMONAS AERUGINOSA | Biomerieux S.A. (FR) | 2002-09-04 | — | — | EP | disclosed |
| WO-2001042491-A2 | NOVEL ENZYMATIC SUBSTRATES FOR DETECTING PSEUDOMONAS AERUGINOSA | BIOMERIEUX S.A. (FR) | 2001-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030044877-A1 | Novel enzymatic substrates for detecting pseudomonas aeruginosa, compositions containing same and method for detecting said species | PEPD, ENPEP, ANPEP | HDAC1 3750/4885MEN1 3504/4885KMT2A 2959/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.