SCHEMBL322623

SCHEMBL322623

O=C(O)[C@](F)(Cc1ccc(O)cc1)N(F)F

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BLM P54132 1/20 0.50
ESR1 P03372 8/20 0.42
CA2 P00918 2/20 0.42
CAMK2A Q9UQM7 1/20 0.42
ESR2 Q92731 7/20 0.39
FNTA P49354 1/20 0.39
FNTB P49356 1/20 0.39
SLC7A5 Q01650 1/20 0.37
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.36
CTBP2 P56545 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.35
HIF1A Q16665 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7316714 0.85 SMN1; SMN2 (0.50) SMN1; SMN2HIF1A
SCHEMBL28369074 0.85 SMN1; SMN2 (0.50) SMN1; SMN2HIF1A
Trifluoroacetic Acid SCHEMBL30392295 0.76 BLM (0.55) BLMESR1CA2CAMK2AESR2
SCHEMBL24253146 0.74 BLM (0.62) BLMESR1CA2CAMK2AESR2
SCHEMBL1906339 0.74 BLM (0.62) BLMESR1CA2CAMK2AESR2
SCHEMBL11226560 0.74 BLM (0.62) BLMESR1CA2CAMK2AESR2
SCHEMBL22074772 0.71 BLM (0.59) BLMESR1CA2CAMK2AESR2
SCHEMBL30887346 0.70 SMN1; SMN2 (0.50) SMN1; SMN2HIF1A
SCHEMBL3736878 0.70 SMN1; SMN2 (0.50) SMN1; SMN2HIF1A
SCHEMBL29112713 0.70 SMN1; SMN2 (0.50) SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1006 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7153931-B1 Forms of membrane transport vector penetratin; a membrane translocation peptide carrier moiety of given amino acid sequence; use in the improved delivery of therapeutic agents into target cells CYCLACEL LIMITED (GB) 2006-12-26 US claimed
US-7101967-B2 Transport vectors CYCLACEL LIMITED (GB) 2006-09-05 US claimed
US-12637491-B2 Antigenic peptides and uses thereof for diagnosing and treating autism THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2026-05-26 US disclosed
EP-4742908-A1 IMPROVED METHODS FOR GOS STABILIZATION IN YOGURT International N&H Denmark ApS (DK) 2026-05-20 EP disclosed
EP-4739330-A1 CONSENSUS PEPTIDES IN HYA FOR USE IN TREATING DEGENERATED JOINTS NuPep AS (NO) 2026-05-13 EP disclosed
EP-4739277-A1 CONSENSUS PEPTIDES IN HYA NuPep AS (NO) 2026-05-13 EP disclosed
EP-4739331-A1 CONSENSUS PEPTIDES IN HYA FOR USE IN VISCOSUPPLEMENTATION NuPep AS (NO) 2026-05-13 EP disclosed
US-12624365-B2 Method for modulating the alkaloid content of a tobacco plant BRITISH AMERICAN TOBACCO (INVESTMENTS) LIMITED (GB) 2026-05-12 US disclosed
EP-4731270-A1 COMBINATION THERAPY WITH PEPTIDE RECEPTOR RADIONUCLIDE AND DNA REPAIR INHIBITOR The Regents of The University of California (US) 2026-04-29 EP disclosed
EP-4727650-A1 ANTI-FIBRIL ANTIBODIES Immutrin Ltd (GB) 2026-04-22 EP disclosed
US-20260071225-A1 BACTERIUM WITH REDUCED SENSITIVITY TO BACTERIOPHAGE DUPONT NUTRITION BIOSCI APS (DK) 2026-03-12 US disclosed
WO-1999054485-A1 A METHOD FOR INHIBITING TUMOR INVASION OR SPREADING IN A SUBJECT THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-10-28 WO disclosed
EP-0938495-A1 COMPOUNDS WHICH PREVENT NEURONAL CELL DEATH AND USES THEREOF The Trustees of Columbia University in the City of New York (US) 1999-09-01 EP disclosed
US-5929042-A NEURONAL CELL CYTOPROTECTIVE OLIGONUCLEOTIDE FOR TREATING NEURODEGENERATIVE DISORDERS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-07-27 US disclosed
WO-1999018986-A1 METHOD FOR INHIBITING THE BINDING OF LOW DENSITY LIPOPROTEIN TO BLOOD VESSEL MATRIX THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-04-22 WO disclosed
WO-1999011283-A1 METHOD FOR TREATING A SUBJECT SUFFERING FROM CONDITIONS ASSOCIATED WITH AN EXTRACELLULAR ZINC SPHINGOMYELINASE THE TRUSTEES OF COLOMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-03-11 WO disclosed
WO-1999007402-A1 METHOD TO PREVENT ACCELERATED ATHEROSCLEROSIS USING (sRAGE) SOLUBLE RECEPTOR FOR ADVANCED GLYCATION ENDPRODUCTS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1999-02-18 WO disclosed
WO-1998038861-A1 ANTISENSE COMPOUNDS WHICH PREVENT CELL DEATH AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-09-11 WO disclosed
WO-1998001145-A1 THERAPEUTIC APPLICATIONS OF T-BAM (CD40L) TECHNOLOGY TO TREAT DISEASES INVOLVING SMOOTH MUSCLE CELLS THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1998-01-15 WO disclosed
WO-1997035876-A1 COMPOUNDS WHICH PREVENT NEURONAL CELL DEATH AND USES THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 1997-10-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637491-B2 Antigenic peptides and uses thereof for diagnosing and treating autism YBX1, ZP1, YBX3 BLM 3983/4885ESR1 4748/4885CA2 1161/4885
US-12624365-B2 Method for modulating the alkaloid content of a tobacco plant INMT, IPO5, IPO9 BLM 2226/4885ESR1 4657/4885CA2 4730/4885
US-20260071225-A1 BACTERIUM WITH REDUCED SENSITIVITY TO BACTERIOPHAGE O60361, UPF1, BPTF BLM 953/4885ESR1 1898/4885CA2 4858/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.