SCHEMBL7316714

SCHEMBL7316714

O=C(O)[C@](F)(Cc1ccccc1)N(F)F

nearest known ligand 0.50

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.50
HIF1A Q16665 1/20 0.50
CES1 P23141 6/20 0.46
FDPS P14324 1/20 0.40
CYP2C19 P33261 2/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
PTPN1 P18031 3/20 0.39
PTPRC P08575 1/20 0.39
CES2 O00748 1/20 0.39
AKR1B1 P15121 1/20 0.39
FAAH O00519 3/20 0.39
CHRM1 P11229 3/20 0.38
CHRM4 P08173 1/20 0.38
CHRM5 P08912 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
CPA1 P15085 1/20 0.38
ARG1 P05089 1/20 0.37
ARG2 P78540 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28369074 1.00 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACES1FDPSCYP2C19
SCHEMBL322623 0.85 BLM (0.50) SMN1; SMN2HIF1A
SCHEMBL3736878 0.85 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACES1FDPSCYP2C19
SCHEMBL30887346 0.85 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACES1FDPSCYP2C19
SCHEMBL29112713 0.85 SMN1; SMN2 (0.50) SMN1; SMN2HIF1ACES1FDPSCYP2C19
SCHEMBL29510761 0.84 SMN1; SMN2 (0.46) SMN1; SMN2HIF1ACES1CYP2C19
SCHEMBL26127150 0.82 SMN1; SMN2 (0.44) SMN1; SMN2HIF1ACES1FDPSCYP2C19
SCHEMBL73702 0.79 FDPS (0.44) SMN1; SMN2HIF1ACES1FDPSPTPN1
SCHEMBL33528430 0.76 L3MBTL1 (0.41) SMN1; SMN2HIF1AL3MBTL1
SCHEMBL5235928 0.75 SMN1; SMN2 (0.57) SMN1; SMN2HIF1ACES1FDPSCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119715853-A Semi-quantitative assessment method for substitution degree of non-protein amino acid 遵义医科大学 2025-03-28 CN claimed
US-6232305-B1 ANTICANCER AGENTS; BONE DISORDERS; ANTIARTHRITIC AGENTS; RESPIRATORY SYSTEM DISORDERS NAEJA PHARMACEUTICAL INC. (CA) 2001-05-15 US claimed
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof GENEFRONTIER CORPORATION (JP) 2026-03-03 US disclosed
US-12534498-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2026-01-27 US disclosed
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY (US) 2026-01-01 US disclosed
US-12371461-B2 Nemo coiled coil mimics and methods of using same NEW YORK UNIVERSITY (US) 2025-07-29 US disclosed
CN-119715853-A Semi-quantitative assessment method for substitution degree of non-protein amino acid 遵义医科大学 2025-03-28 CN disclosed
US-20240279280-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-08-22 US disclosed
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME UNIV NEW YORK (US) 2024-06-13 US disclosed
US-11976137-B2 Compounds for use as apelin receptor antagonists CAMBRIDGE ENTERPRISE LIMITED (GB) 2024-05-07 US disclosed
US-20240092836-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF GENEFRONTIER CORPORATION (JP) 2024-03-21 US disclosed
US-11440938-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2022-09-13 US disclosed
CN-113811278-A Concealment of hypomineralised lesions 墨尔本大学 2021-12-17 CN disclosed
CN-113766904-A Compositions and methods for promoting mineralization 墨尔本大学 2021-12-07 CN disclosed
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS UNIV NEW YORK (US) 2021-09-09 US disclosed
US-20210155659-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS CAMBRIDGE ENTERPRISE LIMITED (GB) 2021-05-27 US disclosed
US-10851133-B2 Stabilized minimal coiled-coil mimetics NEW YORK UNIVERSITY (US) 2020-12-01 US disclosed
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME NEW YORK UNIVERSITY 2020-06-18 US disclosed
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS NEW YORK UNIVERSITY 2018-06-14 US disclosed
CN-107427700-A Mineralising fluoride composition 墨尔本大学 2017-12-01 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092836-A1 CYCLIC PEPTIDE HAVING CTLA-4 INHIBITORY ACTIVITY AND USE THEREOF CXCL10, CXCR3, CXCR6 SMN1; SMN2 4812/4885HIF1A 1502/4885CES1 3977/4885
US-12534498-B2 Compounds for use as apelin receptor antagonists APLNR, NPBWR1, AP3B1 SMN1; SMN2 3681/4885HIF1A 1620/4885CES1 4457/4885
US-12371461-B2 Nemo coiled coil mimics and methods of using same COIL, CALCOCO2, NCAPH SMN1; SMN2 346/4885HIF1A 3368/4885CES1 556/4885
US-12565517-B2 Cyclic peptide having CTLA-4 inhibitory activity and use thereof CXCL10, MLX, MICA SMN1; SMN2 4322/4885HIF1A 1278/4885CES1 3983/4885
US-11440938-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, SMC2 SMN1; SMN2 310/4885HIF1A 2087/4885CES1 3994/4885
US-10851133-B2 Stabilized minimal coiled-coil mimetics COIL, CALCOCO2, CRYZ SMN1; SMN2 188/4885HIF1A 2572/4885CES1 3878/4885
US-11976137-B2 Compounds for use as apelin receptor antagonists APLNR, GIPR, GRPR SMN1; SMN2 4210/4885HIF1A 2109/4885CES1 4433/4885
US-20210277059-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ SMN1; SMN2 188/4885HIF1A 2572/4885CES1 3878/4885
US-20210155659-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS APLNR, GIPR, GRPR SMN1; SMN2 4210/4885HIF1A 2109/4885CES1 4433/4885
US-20260001924-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME DDX21, PHAX, RBX1 SMN1; SMN2 1850/4885HIF1A 1327/4885CES1 1194/4885
US-20200190155-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH SMN1; SMN2 346/4885HIF1A 3368/4885CES1 556/4885
US-20180162907-A1 STABILIZED MINIMAL COILED-COIL MIMETICS COIL, CALCOCO2, CRYZ SMN1; SMN2 188/4885HIF1A 2572/4885CES1 3878/4885
US-20240190930-A1 NEMO COILED COIL MIMICS AND METHODS OF USING SAME COIL, CALCOCO2, NCAPH SMN1; SMN2 352/4885HIF1A 3169/4885CES1 628/4885
US-20240279280-A1 COMPOUNDS FOR USE AS APELIN RECEPTOR ANTAGONISTS APLNR, GIPR, GRPR SMN1; SMN2 4210/4885HIF1A 2109/4885CES1 4433/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.