Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13537412 | 0.89 | EPHX1 (0.31) | — | |
| SCHEMBL17453649 | 0.74 | CHRNB2 (0.32) | — | |
| SCHEMBL17453650 | 0.74 | CHRNB2 (0.32) | — | |
| SCHEMBL31721761 | 0.74 | CHRNB2 (0.32) | — | |
| Hydrochloric Acid SCHEMBL15416120 | 0.73 | CHRNB2 (0.32) | — | |
| SCHEMBL15415008 | 0.72 | POLB (0.38) | PKM | |
| Hydrochloric Acid SCHEMBL16909553 | 0.71 | POLB (0.37) | PKM | |
| Trifluoroacetic Acid SCHEMBL21111207 | 0.70 | PKM (0.34) | SSTR4HRH4HRH3PKM | |
| Trifluoroacetic Acid SCHEMBL29651364 | 0.68 | GABRP (0.45) | HRH4HRH3PKM | |
| Trifluoroacetic Acid SCHEMBL6209474 | 0.68 | GABRP (0.45) | HRH4HRH3PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010007032-A1 | PIPERIDINE BASED UREAS AS NK1 ANTAGONISTS | GLAXO WELLCOME MANUFACTURING PTE LTD (SG) | 2010-01-21 | — | — | WO | disclosed |