Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.63 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.57 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.53 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.53 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.53 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230346 | 0.88 | CXCR2 (0.63) | MAPTCXCR2P2RX1MEN1KMT2A | |
| SCHEMBL3218512 | 0.84 | CXCR2 (0.72) | MAPTCXCR2RAB9ANPC1PTGS1 | |
| SCHEMBL3225340 | 0.83 | CXCR2 (0.71) | CXCR2KCNK3MEN1KMT2ATSHR | |
| SCHEMBL3221810 | 0.83 | ADORA3 (0.63) | MAPTCXCR2KCNK3LMNAP2RX1 | |
| SCHEMBL24141032 | 0.82 | MAPT (0.84) | MAPTRXFP1KCNK3LMNAP2RX1 | |
| SCHEMBL3229652 | 0.82 | NPC1 (0.59) | MAPTCXCR2LMNAP2RX1TSHR | |
| SCHEMBL3220123 | 0.82 | CXCR2 (0.55) | MAPTCXCR2RXFP1LMNAMEN1 | |
| SCHEMBL11791073 | 0.81 | RXFP1 (0.79) | MAPTRXFP1KCNK3LMNAP2RX1 | |
| SCHEMBL23447711 | 0.81 | MAPT (0.82) | MAPTRXFP1KCNK3LMNAP2RX1 | |
| SCHEMBL3223328 | 0.81 | CXCR2 (0.59) | MAPTCXCR2LMNAP2RX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100063105-A1 | PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES | UCB SA (GB) | 2010-03-11 | — | — | US | disclosed |
| US-7141590-B2 | Pharmaceutical uses and synthesis of nicotinanilide-N-oxides | UCB SA (GB) | 2006-11-28 | — | — | US | disclosed |
| US-20050026965-A1 | Pharmaceutical uses and synthesis of nicotinanilide-N-oxides | DARWIN DISCOVERY LIMITED (GB) | 2005-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100063105-A1 | PHARMACEUTICAL USES AND SYNTHESIS OF NICOTINANILIDE-N-OXIDES | NNT, NAPRT, NNMT | MAPT 2060/4885CXCR2 1447/4885RXFP1 3596/4885 |
| US-20050026965-A1 | Pharmaceutical uses and synthesis of nicotinanilide-N-oxides | NNT, NAPRT, NNMT | MAPT 2060/4885CXCR2 1447/4885RXFP1 3596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.