⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3227321 | 0.91 | TDO2 (0.33) | — | |
| SCHEMBL3025398 | 0.88 | — | — | |
| SCHEMBL3221990 | 0.86 | — | — | |
| SCHEMBL1277657 | 0.85 | TDO2 (0.34) | — | |
| SCHEMBL1277661 | 0.85 | TDO2 (0.34) | — | |
| SCHEMBL3222000 | 0.84 | TDO2 (0.32) | — | |
| SCHEMBL3021201 | 0.84 | RIPK1 (0.32) | — | |
| SCHEMBL3021198 | 0.84 | RIPK1 (0.32) | — | |
| SCHEMBL3028047 | 0.84 | TDO2 (0.31) | — | |
| SCHEMBL3028052 | 0.84 | TDO2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2220081-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG Life Sciences Ltd. (KR) | 2010-08-25 | — | — | EP | disclosed |
| WO-2009082152-A2 | GLUCOKINASE ACTIVATORS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS AN ACTIVE INGREDIENT | LG LIFE SCIENCES LTD. (KR) | 2009-07-02 | — | — | WO | disclosed |