Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3230952 | 0.90 | HRH3 (0.41) | TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL3264017 | 0.83 | MAPK1 (0.40) | TSHRMAPK1CTSBKDM4E | |
| SCHEMBL3235712 | 0.79 | HRH3 (0.41) | KDM4E | |
| SCHEMBL3239393 | 0.77 | HRH3 (0.45) | KDM4E | |
| SCHEMBL3238154 | 0.74 | MAPK1 (0.38) | TSHRMAPK1KDM4EALDH1A1 | |
| SCHEMBL3232108 | 0.72 | MAPK1 (0.40) | TSHRMAPK1CTSBKDM4EALDH1A1 | |
| SCHEMBL28384165 | 0.70 | MAPT (0.44) | TSHRKDM4EALDH1A1 | |
| SCHEMBL3232029 | 0.69 | MAPK1 (0.46) | TSHRMAPK1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL10568398 | 0.68 | MAPT (0.62) | TSHRKDM4EALDH1A1 | |
| SCHEMBL3236422 | 0.67 | HRH3 (0.40) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |