Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3235712 | 0.90 | HRH3 (0.41) | HRH3KDM4E | |
| SCHEMBL3227312 | 0.90 | GRM5 (0.35) | KDM4EALDH1A1TSHRMAPK1 | |
| SCHEMBL3239393 | 0.87 | HRH3 (0.45) | HRH3KDM4E | |
| SCHEMBL3264017 | 0.80 | MAPK1 (0.40) | KDM4ETSHRMAPK1 | |
| SCHEMBL3240767 | 0.80 | HRH3 (0.39) | HRH3LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL3236422 | 0.77 | HRH3 (0.40) | HRH3LMNAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL28384165 | 0.71 | MAPT (0.44) | KDM4EALDH1A1TP53TSHRLMNA | |
| SCHEMBL10568398 | 0.69 | MAPT (0.62) | KDM4EALDH1A1TP53TSHRLMNA | |
| SCHEMBL3232108 | 0.69 | MAPK1 (0.40) | KDM4EALDH1A1TSHRLMNAMAPK1 | |
| SCHEMBL3241681 | 0.68 | MEN1 (0.50) | ALDH1A1LMNAMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010029066-A1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS, USE THEREOF AND AGENTS CONTAINING SAID COMPOUNDS | BASF SE (DE) | 2010-03-18 | — | — | WO | disclosed |