Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 10/20 | 0.59 |
| ▸ | GABRG2 | P18507 | 10/20 | 0.59 |
| ▸ | GABRB3 | P28472 | 10/20 | 0.59 |
| ▸ | GABRA5 | P31644 | 10/20 | 0.59 |
| ▸ | GABRA3 | P34903 | 10/20 | 0.59 |
| ▸ | GABRA2 | P47869 | 10/20 | 0.59 |
| ▸ | GABRP | O00591 | 7/20 | 0.59 |
| ▸ | GABRD | O14764 | 7/20 | 0.59 |
| ▸ | GABRB1 | P18505 | 7/20 | 0.59 |
| ▸ | GABRB2 | P47870 | 7/20 | 0.59 |
| ▸ | GABRA4 | P48169 | 7/20 | 0.59 |
| ▸ | GABRE | P78334 | 7/20 | 0.59 |
| ▸ | GABRA6 | Q16445 | 7/20 | 0.59 |
| ▸ | GABRG1 | Q8N1C3 | 7/20 | 0.59 |
| ▸ | GABRG3 | Q99928 | 7/20 | 0.59 |
| ▸ | GABRQ | Q9UN88 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12240630 | 0.84 | GABRA1 (0.69) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL30678031 | 0.75 | IMPDH2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3433644 | 0.75 | IMPDH2 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL12240632 | 0.74 | AHR (0.58) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL3228276 | 0.74 | GABRA1 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL29388457 | 0.74 | GABRA1 (0.59) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20482755 | 0.73 | GABRA1 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| Iodide SCHEMBL9958847 | 0.73 | GABRA1 (0.57) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL20262952 | 0.70 | GABRA1 (0.71) | GABRA1GABRG2GABRB3GABRA5GABRA3 | |
| SCHEMBL18851614 | 0.69 | IMPDH2 (0.52) | GABRA1GABRG2GABRB3GABRA5GABRA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015585-A1 | 6-BENZYL-2,3,4,7-TETRAHYDRO-INDOLO[2,3-C]QUINOLINE COMPOUNDS | NYCOMED GMBH (DE) | 2010-02-11 | — | — | WO | disclosed |