SCHEMBL3433644

SCHEMBL3433644

Nc1cccc2[nH]c3ccccc3c12

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IMPDH2 P12268 1/20 0.59
IMPDH1 P20839 1/20 0.59
ALDH1A1 P00352 5/20 0.54
HSD17B10 Q99714 3/20 0.54
GPR3 P46089 1/20 0.54
GABRP O00591 2/20 0.52
GABRD O14764 2/20 0.52
GABRA1 P14867 2/20 0.52
GABRB1 P18505 2/20 0.52
GABRG2 P18507 2/20 0.52
GABRB3 P28472 2/20 0.52
GABRA5 P31644 2/20 0.52
GABRA3 P34903 2/20 0.52
GABRA2 P47869 2/20 0.52
GABRB2 P47870 2/20 0.52
GABRA4 P48169 2/20 0.52
GABRE P78334 2/20 0.52
GABRA6 Q16445 2/20 0.52
GABRG1 Q8N1C3 2/20 0.52
GABRG3 Q99928 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30678031 1.00 IMPDH2 (0.59) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
Carbazole SCHEMBL9510634 0.86 CDK4 (0.61) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL3420569 0.84 POLB (0.64) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL29519421 0.84 POLB (0.64) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL18851614 0.84 IMPDH2 (0.52) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL3873727 0.84 PSMB8 (0.43) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL5914563 0.81 TDP1 (0.59) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3
SCHEMBL5914561 0.80 CDK4 (0.54) IMPDH2IMPDH1ALDH1A1GABRPGABRD
SCHEMBL5914559 0.80 CDK4 (0.46) IMPDH2IMPDH1GABRPGABRDGABRA1
SCHEMBL3874834 0.79 GABRP (0.53) IMPDH2IMPDH1ALDH1A1HSD17B10GPR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
CN-109232383-B Method for synthesizing 4-bromocarbazole 河南省科学院高新技术研究中心 2022-02-01 CN claimed
CN-109232380-B Synthetic method of 4-bromocarbazole 新乡市润宇新材料科技有限公司 2021-08-10 CN claimed
CN-108947890-B Method for preparing disubstituted 4-aminocarbazole compound 台州学院 2020-08-04 CN claimed
CN-109081807-B Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds 台州学院 2020-08-04 CN claimed
CN-109232383-A A method of synthesis 4- bromine carbazole 河南省科学院高新技术研究中心 2019-01-18 CN claimed
CN-109232380-A A kind of synthetic method of 4- bromine carbazole 新乡市润宇新材料科技有限公司 2019-01-18 CN claimed
CN-109081807-A A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes 台州学院 2018-12-25 CN claimed
CN-108947890-A A method of preparing two substitution 4- aminocarbazole class compounds 台州学院 2018-12-07 CN claimed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP claimed
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN claimed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US claimed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US claimed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP claimed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN claimed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US claimed
EP-0726889-B1 PROCESS FOR PREPARING SUBSTITUTED AROMATIC AMINES MONSANTO CO (US) 2000-04-12 EP claimed
CN-118480063-A Heteropolycyclic aromatic hydrocarbon compound and organic electroluminescent device thereof 吉林省元合电子材料有限公司 2024-08-13 CN disclosed
CN-111349066-B Organic compound, light emitting diode having the same, and light emitting device 乐金显示有限公司 2024-01-23 CN disclosed
WO-2023100891-A1 SOLID MOLTEN MIXTURE, SOLID COMPOSITION, MIXED POWDER, METHOD FOR CHOOSING ORGANIC COMPOUND, METHOD FOR PRODUCING SOLID MOLTEN MIXTURE, AND METHOD FOR PRODUCING ORGANIC ELECTROLUMINESCENT ELEMENT 出光興産株式会社 2023-06-08 WO disclosed
WO-2023013615-A1 AMINE COMPOUND, HOLE INJECTION LAYER AND ORGANIC ELECTROLUMINESCENT ELEMENT 東ソー株式会社 2023-02-09 WO disclosed
CN-115353484-A Synthetic method of 4-amino substituted carbazole, dibenzo [ b, d ] furan and fluorene derivatives 西北师范大学 2022-11-18 CN disclosed
CN-114574223-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal element JSR株式会社 2022-06-03 CN disclosed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP disclosed
CN-109232383-B Method for synthesizing 4-bromocarbazole 河南省科学院高新技术研究中心 2022-02-01 CN disclosed
CN-109232380-B Synthetic method of 4-bromocarbazole 新乡市润宇新材料科技有限公司 2021-08-10 CN disclosed
CN-108947890-B Method for preparing disubstituted 4-aminocarbazole compound 台州学院 2020-08-04 CN disclosed
CN-108947890-B Method for preparing disubstituted 4-aminocarbazole compound 台州学院 2020-08-04 CN disclosed
CN-108947890-B Method for preparing disubstituted 4-aminocarbazole compound 台州学院 2020-08-04 CN disclosed
CN-109081807-B Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds 台州学院 2020-08-04 CN disclosed
CN-109081807-B Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds 台州学院 2020-08-04 CN disclosed
CN-109081807-B Method for preparing tri-substituted 4-aminocarbazole and di-substituted 1-aminodibenzo [ b, d ] thiophene compounds 台州学院 2020-08-04 CN disclosed
US-10557210-B2 Direct electrochemical synthesis of doped conductive polymers on metal alloys THE BOEING COMPANY (US) 2020-02-11 US disclosed
EP-3366690-B1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE ORGANOMETALLIC COMPOUND, AND DIAGNOSTIC COMPOSITION INCLUDING THE ORGANOMETALLIC COMPOUND SAMSUNG ELECTRONICS CO LTD (KR) 2020-01-29 EP disclosed
CN-104862756-B The conducting polymer of Direct Electrochemistry synthesis doping on metal alloy 波音公司 2019-05-03 CN disclosed
US-10193070-B2 Electroactive materials E I DU PONT DE NEMOURS AND COMPANY (US) 2019-01-29 US disclosed
CN-109232380-A A kind of synthetic method of 4- bromine carbazole 新乡市润宇新材料科技有限公司 2019-01-18 CN disclosed
CN-109232383-A A method of synthesis 4- bromine carbazole 河南省科学院高新技术研究中心 2019-01-18 CN disclosed
CN-109081807-A A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes 台州学院 2018-12-25 CN disclosed
CN-109081807-A A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes 台州学院 2018-12-25 CN disclosed
CN-109081807-A A kind of three substitution 4- aminocarbazole classes and two that prepare replace the method for 1- aminodiphenyls simultaneously [b, d] thiophenes 台州学院 2018-12-25 CN disclosed
CN-108947890-A A method of preparing two substitution 4- aminocarbazole class compounds 台州学院 2018-12-07 CN disclosed
CN-108947890-A A method of preparing two substitution 4- aminocarbazole class compounds 台州学院 2018-12-07 CN disclosed
CN-108947890-A A method of preparing two substitution 4- aminocarbazole class compounds 台州学院 2018-12-07 CN disclosed
EP-3396028-A2 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS The Boeing Company (US) 2018-10-31 EP disclosed
EP-3221294-B1 HETEROCYCLIC COMPOUNDS FOR USE IN ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2018-09-05 EP disclosed
EP-2910668-B1 Direct electrochemical synthesis of doped conductive polymers on metal alloys BOEING CO (US) 2018-04-11 EP disclosed
US-20170229654-A1 ELECTROACTIVE MATERIALS LG CHEM, LTD. (KR) 2017-08-10 US disclosed
EP-2991128-B1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG ELECTRONICS CO LTD (KR) 2017-04-12 EP disclosed
EP-2772483-B1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME TOSOH CORP (JP) 2017-03-29 EP disclosed
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN disclosed
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN disclosed
CN-104011022-B 4-aminocarbazole compound and application thereof 东曹株式会社 2016-08-24 CN disclosed
CN-103477463-B Organic illuminating element, organometallic complex, light-emitting device, electronic equipment and illuminator 株式会社半导体能源研究所 2016-08-10 CN disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
US-9172045-B2 4-aminocarbazole compound and use thereof TOSOH CORPORATION (JP) 2015-10-27 US disclosed
CN-104974166-A Organic electroluminescent material and device UNIVERSAL DISPLAY CORP 2015-10-14 CN disclosed
US-20150240378-A1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS THE BOEING COMPANY (US) 2015-08-27 US disclosed
EP-2910668-A2 Direct electrochemical synthesis of doped conductive polymers on metal alloys The Boeing Company (US) 2015-08-26 EP disclosed
CN-104862756-A Direct electrochemical synthesis of doped conductive polymers on metal alloys BOEING CO 2015-08-26 CN disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
US-20140296519-A1 4-AMINOCARBAZOLE COMPOUND AND USE THEREOF TOSOH CORPORATION (JP) 2014-10-02 US disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
EP-2772483-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME Tosoh Corporation (JP) 2014-09-03 EP disclosed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN disclosed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN disclosed
CN-104011022-A 4-aminocarbazole compound and use of same TOSOH CORP 2014-08-27 CN disclosed
WO-2013062043-A1 4-AMINOCARBAZOLE COMPOUND AND USE OF SAME 東ソー株式会社 (JP) 2013-05-02 WO disclosed
WO-2010027280-A1 NITROBENZINDOLES AND THEIR USE IN CANCER THERAPY AUCKLAND UNISERVICES LIMITED (NZ) 2010-03-11 WO disclosed
US-7491245-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2009-02-17 US disclosed
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof GLENN ROBERT W JR 2008-05-01 US disclosed
US-7331997-B2 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof THE PROCTER & GAMBLE COMPANY (US) 2008-02-19 US disclosed
CN-1937994-A Keratin dyeing compounds, keratin dyeing compositions containing them and their use PROCTER & GAMBLE (US) 2007-03-28 CN disclosed
EP-1735059-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF The Procter and Gamble Company (US) 2006-12-27 EP disclosed
WO-2005099656-A2 KERATIN DYEING COMPOUNDS, KERATIN DYEING COMPOSITIONS CONTAINING THEM, AND USE THEREOF THE PROCTER & GAMBLE COMPANY (US) 2005-10-27 WO disclosed
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof PROCTER & GAMBLE COMPANY, THE 2005-10-06 US disclosed
US-6818118-B2 FOR FORMING CORROSION-RESISTANT COATINGS ON ALUMINUM MCDONNELL DOUGLAS CORPORATION 2004-11-16 US disclosed
US-20040020784-A1 ANODICALLY FORMED INTRINSICALLY CONDUCTIVE POLYMER-ALUMINUM OXIDE COMPOSITE AS A COATING ON ALUMINUM MCDONNELL DOUGLAS CORPORATION 2004-02-05 US disclosed
EP-1227111-A1 TRIPHENYLBORON-CONTAINING POLYMERS AND USE THEREOF Yoshitomi Fine Chemicals, Ltd. (JP) 2002-07-31 EP disclosed
US-6380346-B1 HIGH SOLUBILITY AND/OR HIGH PROCESSIBILITY; TREATMENT WITH A SOLUTION OF REACTIVE CHEMICAL REAGENT(S), E.G. MERCAPTAN, IN A SELECTED SOLVENT; FUNCTIONALIZING THE SOLID POLYANILINE AND TRANSFORMING THE BACKBONE INTO A MORE REDUCED FORM NATIONAL TSING HUA UNIVERSITY (TW) 2002-04-30 US disclosed
US-6328874-B1 FORMING A COATING ON ALUMINUM BY CONTACTING WITH WATER, POLYMERIC ORGANIC ACID, A MONOMER OF INTRINSICALLY CONDUCTIVE POLYMER AND POLYMERIZING MONOMER BY IMPOSING ELECTRICAL POTENTIAL TO FORM CORROSION PROTECTIVE COATING MCDONNELL DOUGLAS CORPORATION 2001-12-11 US disclosed
US-6228492-B1 SPINNING; BUNDLING ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 2001-05-08 US disclosed
EP-0939841-A1 PREPARATION OF FIBERS CONTAINING INTRINSICALLY CONDUCTIVE POLYMERS Zipperling Kessler & Co (GmbH & Co) (DE) 1999-09-08 EP disclosed
WO-1999035308-A2 ANODICALLY FORMED INTRINSICALLY CONDUCTIVE POLYMER-ALUMINUM OXIDE COMPOSITE AS A COATING ON ALUMINUM ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-07-15 WO disclosed
WO-1999025778-A1 SYNTHESIS AND APPLICATIONS OF INTRINSICALLY CONDUCTIVE POLYMER SALTS OF POLYPHOSPHONIC ACIDS IN ANTI-CORROSION COATINGS ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-05-27 WO disclosed
WO-1999015725-A1 PREPARATION OF FIBERS CONTAINING INTRINSICALLY CONDUCTIVE POLYMERS ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-01 WO disclosed
WO-1999016084-A1 ELECTRICALLY CONDUCTIVE BLOCK COPOLYMERS CONTAINING AN INTRINSICALLY CONDUCTIVE POLYMER ZIPPERLING KESSLER & CO. (GMBH & CO.) (DE) 1999-04-01 WO disclosed
US-5763374-A ACRYLATE-METHACRYLATE COPOLYMER FOR REDUCING HIGH TEMPERATURE VISCOSITY SANYO CHEMICAL INDUSTRIES, LTD. (JP) 1998-06-09 US disclosed
US-5446011-A Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid RICOH COMPANY, LTD. (JP) 1995-08-29 US disclosed
US-5446011-A Imagewise coloring when heating; mixture of n-substituted indole, aromatic polyhydroxy compound, carbonyl compound and an acid RICOH COMPANY, LTD. (JP) 1995-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050217038-A1 Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof KRT18, CKMT1A; CKMT1B, TUBB6 IMPDH2 2923/4885IMPDH1 2771/4885ALDH1A1 660/4885
US-10193070-B2 Electroactive materials EPX, INA, KCNN2 IMPDH2 3421/4885IMPDH1 3726/4885ALDH1A1 476/4885
US-20170229654-A1 ELECTROACTIVE MATERIALS EPX, INA, KCNN2 IMPDH2 3421/4885IMPDH1 3726/4885ALDH1A1 476/4885
US-20080098535-A1 Keratin Dyeing Compounds, Keratin Dyeing Compositions Containing Them, And Use Thereof KRT18, CKMT1A; CKMT1B, TUBB6 IMPDH2 2923/4885IMPDH1 2771/4885ALDH1A1 660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.