Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | CSGALNACT1 | Q8TDX6 | 11/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.49 |
| ▸ | RELA | Q04206 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2298617 | 0.96 | RAB9A (0.57) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3237097 | 0.92 | RAB9A (0.52) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2297791 | 0.89 | RAB9A (0.58) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2293812 | 0.87 | SMN1; SMN2 (0.57) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2297887 | 0.84 | MAPT (0.62) | RAB9ASMN1; SMN2MEN1KMT2ACSGALNACT1 | |
| SCHEMBL2297570 | 0.84 | CSGALNACT1 (0.56) | RAB9ASMN1; SMN2MEN1KMT2ACSGALNACT1 | |
| SCHEMBL3231890 | 0.82 | SMN1; SMN2 (0.52) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL3237048 | 0.81 | CSGALNACT1 (0.67) | CSGALNACT1 | |
| SCHEMBL2299999 | 0.78 | MEN1 (0.60) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E | |
| SCHEMBL2298410 | 0.78 | CSGALNACT1 (0.56) | RAB9ASMN1; SMN2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |