Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | CSGALNACT1 | Q8TDX6 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2293812 | 0.95 | SMN1; SMN2 (0.57) | SMN1; SMN2KDM4EMAPTCSGALNACT1MEN1 | |
| SCHEMBL3237097 | 0.90 | RAB9A (0.52) | SMN1; SMN2KDM4EMAPTCSGALNACT1MEN1 | |
| SCHEMBL2294258 | 0.87 | LMNA (0.54) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2297887 | 0.85 | MAPT (0.62) | SMN1; SMN2MAPTCSGALNACT1MEN1KMT2A | |
| SCHEMBL2298617 | 0.84 | RAB9A (0.57) | SMN1; SMN2KDM4EMAPTCSGALNACT1MEN1 | |
| SCHEMBL3227975 | 0.82 | RAB9A (0.53) | SMN1; SMN2KDM4EMAPTCSGALNACT1MEN1 | |
| SCHEMBL892695 | 0.82 | SMN1; SMN2 (0.58) | SMN1; SMN2KDM4EMAPTMEN1KMT2A | |
| SCHEMBL2299999 | 0.78 | MEN1 (0.60) | SMN1; SMN2KDM4ECSGALNACT1MEN1KMT2A | |
| SCHEMBL2299194 | 0.78 | NPC1 (0.57) | SMN1; SMN2MAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL2297570 | 0.77 | CSGALNACT1 (0.56) | SMN1; SMN2MAPTCSGALNACT1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |