Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938078 | 0.85 | TRPA1 (0.54) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL9478908 | 0.81 | ALDH1A1 (0.50) | MAPTGAAKDM4ETDP1RECQL | |
| SCHEMBL29720861 | 0.81 | CXCR2 (0.68) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL1008928 | 0.81 | CXCR2 (0.68) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL30594032 | 0.79 | MEN1 (0.58) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL429858 | 0.79 | MEN1 (0.58) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL27294589 | 0.79 | MAPT (0.56) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL28651741 | 0.79 | ALDH1A1 (0.49) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL27435565 | 0.79 | CXCR2 (0.66) | MAPTMEN1KMT2AGAAKDM4E | |
| SCHEMBL28044335 | 0.77 | MAPT (0.50) | MAPTMEN1KMT2AGAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4745145-A | AMINE COMPOUNDS WHICH IMPROVE ADHESION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-05-17 | — | — | US | claimed |
| EP-0137987-B1 | RUBBER COMPOSITIONS AND ARTICLES THEREOF HAVING IMPROVED METAL ADHESION AND METAL ADHESION RETENTION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-09-30 | — | — | EP | claimed |
| EP-0137987-A1 | Rubber compositions and articles thereof having improved metal adhesion and metal adhesion retention | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-04-24 | — | — | EP | claimed |
| CN-110551241-B | Preparation method of flame-retardant polyolefin and product thereof | 安徽工大化工科技有限公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-110551241-A | Preparation method of flame-retardant polyolefin and product thereof | ANHUI GONGDA CHEMICAL TECH CO LTD | 2019-12-10 | — | — | CN | disclosed |
| EP-2807159-A1 | NEW INDOLIZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | Les Laboratoires Servier (FR) | 2014-12-03 | — | — | EP | disclosed |
| WO-2013110890-A1 | NEW INDOLIZINE DERIVATIVES, METHOD FOR PREPARING SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | LES LABORATOIRES SERVIER (FR) | 2013-08-01 | — | — | WO | disclosed |
| WO-2010017673-A1 | RESORCINOL AND M-AMINOPHENOL DERIVATIVES BLENDS IN RUBBER COMPOUNDING APPLICATIONS | SINO LEGEND (ZHANGJIAGANG) CHEMICAL CO., LTD (CN) | 2010-02-18 | — | — | WO | disclosed |
| US-4745145-A | AMINE COMPOUNDS WHICH IMPROVE ADHESION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-05-17 | — | — | US | disclosed |
| US-4745145-A | AMINE COMPOUNDS WHICH IMPROVE ADHESION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1988-05-17 | — | — | US | disclosed |
| EP-0137987-B1 | RUBBER COMPOSITIONS AND ARTICLES THEREOF HAVING IMPROVED METAL ADHESION AND METAL ADHESION RETENTION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1987-09-30 | — | — | EP | disclosed |
| EP-0137987-A1 | Rubber compositions and articles thereof having improved metal adhesion and metal adhesion retention | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0137987-A1 | Rubber compositions and articles thereof having improved metal adhesion and metal adhesion retention | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0137986-A1 | Method for improving rubber-to-metal adhesion and adhesion retention | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1985-04-24 | — | — | EP | disclosed |
| EP-0011254-B1 | PROCESS FOR THE PREPARATION OF HYDRO-DIPHENYL AMINES | BAYER AG (DE) | 1982-01-13 | — | — | EP | disclosed |
| US-4265833-A | CATALYTIC AMINATION OF A DIHYDROXYBENZENE WITH A PRIMARY AROMATIC AMINE | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-05 | — | — | US | disclosed |
| EP-0011254-A1 | Process for the preparation of hydro-diphenyl amines | BAYER AG (DE) | 1980-05-28 | — | — | EP | disclosed |