Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 16/20 | 0.62 |
| ▸ | CHRNA4 | P43681 | 16/20 | 0.62 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.48 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL718760 | 0.94 | CHRNB2 (0.58) | CHRNB2CHRNA4CHEK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1769584 | 0.92 | CHRNB2 (0.57) | CHRNB2CHRNA4CHEK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL29882337 | 0.92 | CHRNB2 (0.57) | CHRNB2CHRNA4CHEK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL23303948 | 0.92 | CHRNB2 (0.57) | CHRNB2CHRNA4CHEK1DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL23303548 | 0.92 | CHRNB2 (0.57) | CHRNB2CHRNA4CHEK1DRD2DRD3 | |
| SCHEMBL27909230 | 0.86 | CHRNB2 (0.44) | CHRNB2CHRNA4CHEK1 | |
| SCHEMBL151047 | 0.86 | MAPT (0.46) | CHRNB2CHRNA4 | |
| SCHEMBL151160 | 0.84 | MAPT (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL148390 | 0.84 | MAPT (0.49) | CHRNB2CHRNA4 | |
| SCHEMBL24989033 | 0.82 | CHRNB2 (0.49) | CHRNB2CHRNA4CHEK1DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2010-06-10 | — | — | US | disclosed |
| EP-2167490-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | Korea Research Institute Of Chemical Technology (KR) | 2010-03-31 | — | — | EP | disclosed |
| WO-2008153325-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2008-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100144712-A1 | TRIAZOLE DERIVATIVES HAVING ANTIFUNGAL ACTIVITY, METHOD FOR THE PREPARATION THEREOF, AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | CYP51A1, ERG28, CYP3A7 | CHRNB2 4863/4885CHRNA4 4851/4885CHEK1 2928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.