Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 5/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | VDR | P11473 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8584023 | 0.88 | SLC9A1 (0.50) | SLC9A1VCAM1KDM4E | |
| SCHEMBL1763058 | 0.87 | SLC9A1 (0.53) | SLC9A1THRBKDM4E | |
| SCHEMBL8584027 | 0.85 | SLC9A1 (0.48) | SLC9A1VCAM1KDM4E | |
| SCHEMBL8581977 | 0.85 | SLC9A1 (0.48) | SLC9A1VCAM1KDM4E | |
| SCHEMBL8581253 | 0.84 | SLC9A1 (0.47) | SLC9A1VCAM1KDM4EALDH1A1 | |
| SCHEMBL1843131 | 0.82 | SLC9A1 (0.46) | SLC9A1VCAM1 | |
| SCHEMBL1763553 | 0.77 | SLC9A1 (0.54) | SLC9A1THRBKDM4EALDH1A1 | |
| SCHEMBL17398128 | 0.74 | QDPR (0.45) | KDM4EALDH1A1LMNA | |
| SCHEMBL8585395 | 0.74 | SLC9A1 (0.39) | SLC9A1VCAM1KDM4EALDH1A1 | |
| SCHEMBL8578049 | 0.74 | ALDH1A1 (0.43) | SLC9A1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010005783-A1 | PYRROLIDINYL AND PIPERIDINYL COMPOUNDS USEFUL AS NHE-1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-14 | — | — | WO | disclosed |