Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | GNAI3 | P08754 | 3/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 3/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22857557 | 0.90 | HRH3 (0.46) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL22857504 | 0.89 | HRH3 (0.45) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL21392491 | 0.88 | LTA4H (0.45) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL19185581 | 0.88 | LTA4H (0.45) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL19185652 | 0.88 | LTA4H (0.45) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL19185641 | 0.88 | LTA4H (0.45) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL27373431 | 0.88 | GNAI3 (0.53) | GNAI3GNAO1GNAI1LMNAKDM4E | |
| SCHEMBL21361903 | 0.86 | LTA4H (0.40) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL19185680 | 0.86 | LTA4H (0.44) | HRH3GNAI3GNAO1GNAI1LTA4H | |
| SCHEMBL25064562 | 0.84 | LMNA (0.43) | HRH3GNAI3GNAO1GNAI1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100178333-A1 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2010-07-15 | — | — | US | disclosed |
| EP-1976487-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | Astron Research Limited (IN) | 2008-10-08 | — | — | EP | disclosed |
| WO-2007086079-A2 | SUSTAINED RELEASE DOSAGE FORM OF PHENOTHIAZINE DERIVATIVES CONTAINING CHANNELIZER | ASTRON RESEARCH LIMITED (IN) | 2007-08-02 | — | — | WO | disclosed |
| US-4933346-A | CARDIOVASCULAR AND CEREBROVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-12 | — | — | US | disclosed |
| US-4918073-A | CALCIUM ANTAGONISTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-04-17 | — | — | US | disclosed |