Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4673064 | 0.91 | AGBL2 (0.37) | AGBL2 | |
| SCHEMBL2172358 | 0.91 | AGBL2 (0.37) | AGBL2 | |
| SCHEMBL1396051 | 0.82 | AGBL2 (0.38) | AGBL2 | |
| SCHEMBL29877399 | 0.82 | AGBL2 (0.38) | AGBL2 | |
| Hydrochloric Acid SCHEMBL1396013 | 0.81 | TDP1 (0.37) | AGBL2 | |
| Hydrochloric Acid SCHEMBL3233626 | 0.81 | TDP1 (0.37) | AGBL2 | |
| SCHEMBL3941706 | 0.80 | AGBL2 (0.31) | AGBL2 | |
| SCHEMBL4973249 | 0.70 | AGBL2 (0.41) | AGBL2 | |
| SCHEMBL357848 | 0.69 | AGBL2 (0.39) | AGBL2 | |
| SCHEMBL1395992 | 0.69 | AGBL2 (0.40) | AGBL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010020810-A1 | 2-(IMIDAZ0LYLAMIN0)-PYRIDINE DERIVATIVES AND THEIR USE AS JAK KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2010-02-25 | — | — | WO | disclosed |