Ademetionine

Ademetionine

SCHEMBL3229444

C[S+](CCC(N)C(=O)[O-])C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O.O=S(=O)(O)CCCCS(=O)(=O)O

nearest known ligand 0.86

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.86
PCMT1 P22061 3/20 0.86
PRMT5 O14744 2/20 0.86
PRMT1 Q99873 2/20 0.86
NSD3 Q9BZ95 2/20 0.86
PRMT3 O60678 1/20 0.86
ADORA3 P0DMS8 1/20 0.86
PNMT P11086 1/20 0.86
KDR P35968 1/20 0.86
PRMT6 Q96LA8 1/20 0.86
WDR77 Q9BQA1 1/20 0.86
PRMT8 Q9NR22 1/20 0.86
PRMT7 Q9NVM4 1/20 0.86
AMD1 P17707 6/20 0.75
FASN P49327 2/20 0.59
NNMT P40261 2/20 0.57
NSD2 O96028 2/20 0.54
DOT1L Q8TEK3 2/20 0.54
SETD7 Q8WTS6 2/20 0.54
TRDMT1 O14717 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ademetionine SCHEMBL30034534 1.00 CARM1 (0.86) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL25176 0.93 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1300198 0.93 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL29355793 0.93 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1300205 0.93 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL4747876 0.92 CARM1 (0.98) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1980696 0.92 CARM1 (0.98) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL5465751 0.92 CARM1 (0.88) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL5463109 0.90 CARM1 (0.85) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL3685223 0.89 CARM1 (0.83) CARM1PCMT1PRMT5PRMT1NSD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240316089-A1 COMBINATIONS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS KetaMed MSO, LLC 2024-09-26 US claimed
EP-3071191-B1 SLOW-RELEASE SOLID ORAL COMPOSITIONS GNOSIS SPA (IT) 2022-01-05 EP claimed
WO-2021212995-A1 ANTI-AGEING COMPOSITION, DRUG AND HEALTHCARE PRODUCT COMPRISING SAME, AND APPLICATION THEREFOR 百瑞全球有限公司 (VG) 2021-10-28 WO claimed
CN-113521090-A Anti-aging composition, medicine and health product containing anti-aging composition, and application of anti-aging composition 百瑞全球有限公司 2021-10-22 CN claimed
US-10702482-B2 Slow-release solid oral compositions GNOSIS SPA (IT) 2020-07-07 US claimed
CN-105764493-B Sustained release solid oral compositions 灵知股份公司 2020-02-21 CN claimed
US-20160287519-A1 SLOW-RELEASE SOLID ORAL COMPOSITIONS GNOSIS SPA (IT) 2016-10-06 US claimed
WO-2024197234-A1 COMBINATIONS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS KetaMed MSO, LLC (US) 2024-09-26 WO disclosed
US-20240316089-A1 COMBINATIONS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS KetaMed MSO, LLC 2024-09-26 US disclosed
CN-115039845-A Feed additive for improving weight and slaughtering performance of laying hens as well as preparation method and application of feed additive 北京君德同创生物技术股份有限公司 2022-09-13 CN disclosed
CN-114099456-A Capsule containing S-adenosylmethionine and preparation method and application thereof 郑州大学 2022-03-01 CN disclosed
EP-3071191-B1 SLOW-RELEASE SOLID ORAL COMPOSITIONS GNOSIS SPA (IT) 2022-01-05 EP disclosed
WO-2021212995-A1 ANTI-AGEING COMPOSITION, DRUG AND HEALTHCARE PRODUCT COMPRISING SAME, AND APPLICATION THEREFOR 百瑞全球有限公司 (VG) 2021-10-28 WO disclosed
US-20100055218-A1 NOVEL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2010-03-04 US disclosed
US-20100056463-A1 NOVEL COMPOSITIONS DSM IP ASSETS B.V. (NL) 2010-03-04 US disclosed
EP-2049134-A2 COMPOSITIONS COMPRISING ROSEHIP AND OTHER ACTIVE AGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS DSMIP Assets B.V. (NL) 2009-04-22 EP disclosed
EP-2040696-A2 COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF INFLAMMATORY DISORDERS DSMIP Assets B.V. (NL) 2009-04-01 EP disclosed
WO-2008006581-A2 COMPOSITIONS AND USE THEREOF FOR THE TREATMENT, CO-TREATMENT OR PREVENTION OF IMFLAMMATORY DISORDERS DSM IP ASSETS B.V. (NL) 2008-01-17 WO disclosed
WO-2008006582-A1 COMPOSITIONS COMPRISING MAGNOLOL OR HONOKIOL AND OTHER ACTIVE AGENTS FOR THE TREATMENT OF INFLAMMATORY DISEASES DSM IP ASSETS B.V. (NL) 2008-01-17 WO disclosed
WO-2008006589-A2 COMPOSITIONS COMPRISING ROSEHIP AND OTHER ACTIVE AGENTS FOR THE TREATMENT OF INFLAMMATORY DISORDERS DSM IP ASSETS B.V. (NL) 2008-01-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240316089-A1 COMBINATIONS FOR THE TREATMENT OF NEUROLOGICAL CONDITIONS GRIN3A, GRIN2A, GRIN2B CARM1 909/4885PCMT1 416/4885PRMT5 225/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.