Ademetionine

Ademetionine

SCHEMBL5465751

C[S+](CCC(N)C(=O)[O-])C[C@H]1O[C@@H](n2cnc3c(N)ncnc32)[C@H](O)[C@@H]1O.O=S(=O)(O)OS(=O)(=O)O

nearest known ligand 0.88

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CARM1 Q86X55 3/20 0.88
PCMT1 P22061 3/20 0.88
PRMT5 O14744 2/20 0.88
PRMT1 Q99873 2/20 0.88
NSD3 Q9BZ95 2/20 0.88
PRMT3 O60678 1/20 0.88
ADORA3 P0DMS8 1/20 0.88
PNMT P11086 1/20 0.88
KDR P35968 1/20 0.88
PRMT6 Q96LA8 1/20 0.88
WDR77 Q9BQA1 1/20 0.88
PRMT8 Q9NR22 1/20 0.88
PRMT7 Q9NVM4 1/20 0.88
AMD1 P17707 8/20 0.77
FASN P49327 1/20 0.57
NNMT P40261 2/20 0.55
NSD2 O96028 2/20 0.55
DOT1L Q8TEK3 2/20 0.55
SETD7 Q8WTS6 2/20 0.55
TRDMT1 O14717 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ademetionine SCHEMBL10400453 0.94 CARM1 (0.77) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1228179 0.94 CARM1 (0.77) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL29355793 0.94 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1300198 0.94 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL25176 0.94 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1300205 0.94 CARM1 (1.00) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL1980696 0.93 CARM1 (0.98) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL4747876 0.93 CARM1 (0.98) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL3229444 0.92 CARM1 (0.86) CARM1PCMT1PRMT5PRMT1NSD3
Ademetionine SCHEMBL30034534 0.92 CARM1 (0.86) CARM1PCMT1PRMT5PRMT1NSD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007013987-A2 SUPPLEMENT COMPOSITION AND METHOD OF USE IN ENHANCEMENT OF METHYLATION PROCESS SURACELL, INC. (US) 2007-02-01 WO claimed
US-20070021376-A1 Supplement composition and method of use in enhancement of methylation process SURACELL, INC. (US) 2007-01-25 US claimed
US-4956173-A COSMETICS, DRUGS SOCIETE ANONYME: SANOFI (FR) 1990-09-11 US claimed
JP-1193206-A None JP disclosed
CN-121243088-A Preparation process of paratoluenesulfonic acid ademetionine disulfate particles 山东金城生物药业有限公司 2026-01-02 CN disclosed
CN-121243088-A Preparation process of paratoluenesulfonic acid ademetionine disulfate particles 山东金城生物药业有限公司 2026-01-02 CN disclosed
WO-2023228167-A2 SOLID FOOD OR PHARMACEUTICAL FORMULATION, METHODS FOR OBTAINING AND DRYING IT AND ITS USES IN PHARMACEUTICAL, NUTRACEUTICAL OR VETERINARY PRODUCTS DE ANGELIS CARLO (IT) 2023-11-30 WO disclosed
WO-2007013987-A2 SUPPLEMENT COMPOSITION AND METHOD OF USE IN ENHANCEMENT OF METHYLATION PROCESS SURACELL, INC. (US) 2007-02-01 WO disclosed
US-20070021376-A1 Supplement composition and method of use in enhancement of methylation process SURACELL, INC. (US) 2007-01-25 US disclosed
US-6759395-B2 ENTERIC COATINGS ORCHID CHEMICALS & PHARMACEUTICALS, LTD. (IN) 2004-07-06 US disclosed
US-20020164369-A1 Novel soft-gelatin capsule comprising S-adenosylmethionine and a method for producing the same RAO CANAKAPALLI BHAKTAVATSALA (IN) 2002-11-07 US disclosed
WO-2002049637-A1 A NOVEL SOFT-GELATIN CAPSULE COMPRISING S-ADENOSYLMETHIONINE AND A METHOD FOR PRODUCING THE SAME ORCHID CHEMICALS AND PHARMACEUTICALS LIMITED (IN) 2002-06-27 WO disclosed
US-4956173-A COSMETICS, DRUGS SOCIETE ANONYME: SANOFI (FR) 1990-09-11 US disclosed
JP-H01193206-A USE OF ADEMETIONINE TO SENILE CHANGE OF SKIN SANOFI SA 1989-08-03 JP disclosed
EP-0318393-A1 Use of ademetionine against ageing of the skin ELF SANOFI (FR) 1989-05-31 EP disclosed