Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 12/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 3/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | GALR3 | O60755 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.41 |
| ▸ | METTL3 | Q86U44 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737291 | 0.88 | ADK (0.52) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL4428509 | 0.88 | ADK (0.65) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL3229218 | 0.88 | ADK (0.49) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL1735824 | 0.88 | ADK (0.65) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL1737689 | 0.88 | ADK (0.49) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL3229656 | 0.86 | ADK (0.55) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL3229639 | 0.86 | ADK (0.55) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL3234421 | 0.86 | ADK (0.50) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL3234392 | 0.86 | ADK (0.50) | ADKDOT1LADORA2ANPC1GALR3 | |
| SCHEMBL13495010 | 0.86 | ADK (0.50) | ADKDOT1LADORA2ANPC1GALR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015637-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015637-A1 | NEW ANTIVIRAL MODIFIED NUCLEOSIDES | NOVARTIS AG (CH) | 2010-02-11 | — | — | WO | disclosed |