Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL668320 | 0.81 | SLC6A4 (0.33) | ALDH1A1LIPG | |
| SCHEMBL580069 | 0.81 | LIPG (0.33) | LIPG | |
| SCHEMBL840344 | 0.78 | TSHR (0.35) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL9274789 | 0.77 | TSHR (0.36) | — | |
| SCHEMBL29489866 | 0.76 | LIPG (0.48) | ALDH1A1HPGDLIPG | |
| SCHEMBL2340536 | 0.76 | LIPG (0.48) | ALDH1A1HPGDLIPG | |
| SCHEMBL14645439 | 0.75 | KDM4E (0.37) | ALDH1A1 | |
| SCHEMBL5899432 | 0.75 | TSHR (0.36) | ALDH1A1HPGD | |
| SCHEMBL3234120 | 0.74 | ENPP2 (0.37) | LIPG | |
| SCHEMBL22684752 | 0.73 | ENPP2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010010184-A1 | [1, 2, 4] TRIAZOLO [1, 5-A] PYRIDINES AS JAK INHIBITORS | GALAPAGOS NV (BE) | 2010-01-28 | — | — | WO | disclosed |