Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6262091 | 0.82 | SMN1; SMN2 (0.38) | ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL3729308 | 0.80 | SMN1; SMN2 (0.40) | ALDH1A1MAPK1SMN1; SMN2POLBMCOLN3 | |
| SCHEMBL23583482 | 0.80 | ALDH1A1 (0.66) | ALDH1A1MAPK1SMN1; SMN2POLBKDM4E | |
| SCHEMBL31518023 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL26608574 | 0.79 | SMN1; SMN2 (0.53) | ALDH1A1MAPK1SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL27666145 | 0.78 | MCL1 (0.42) | ALDH1A1SMN1; SMN2MCOLN3KMT2AHTT | |
| SCHEMBL5843974 | 0.77 | ALDH1A1 (0.50) | ALDH1A1MAPK1SMN1; SMN2POLB | |
| SCHEMBL6259709 | 0.75 | KCNQ3 (0.52) | ALDH1A1SMN1; SMN2POLBKMT2AMEN1 | |
| SCHEMBL14661145 | 0.75 | POLB (0.47) | ALDH1A1MAPK1SMN1; SMN2POLBKMT2A | |
| SCHEMBL3625286 | 0.74 | KMT2A (0.53) | ALDH1A1POLBKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078906-A2 | HYDRAZIDES METHOD FOR PRODUCTION AND USE THEREOF AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |
| WO-2010009847-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147919-A1 | Heterocyclic substituted amides, method for their manufacture and their use as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |
| WO-2005070889-A1 | HERBICIDAL AMIDES | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-08-04 | — | — | WO | disclosed |