Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | CASP6 | P55212 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | NPY2R | P49146 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13215464 | 0.91 | PLA2G2A (0.57) | PLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL8231553 | 0.83 | PLA2G2A (0.50) | PLA2G2ATP53TSHRNR1H4PLA2G4B | |
| SCHEMBL8231851 | 0.83 | THRB (0.50) | PLA2G2ATP53TSHRPLA2G4B | |
| SCHEMBL4850809 | 0.82 | KDM4E (0.50) | PLA2G2AL3MBTL1LMNATP53TSHR | |
| SCHEMBL13215218 | 0.82 | PLA2G2A (0.49) | PLA2G2ATP53TSHRKDM4EPLA2G4B | |
| SCHEMBL30446490 | 0.81 | TP53 (0.51) | KMT2APLA2G2AL3MBTL1LMNATP53 | |
| SCHEMBL4963556 | 0.81 | TP53 (0.51) | KMT2APLA2G2AL3MBTL1LMNATP53 | |
| SCHEMBL13185967 | 0.81 | LMNA (0.50) | KMT2AL3MBTL1LMNATSHRPLK1 | |
| SCHEMBL9712657 | 0.81 | KMT2A (0.57) | KMT2AL3MBTL1LMNAMEN1ALDH1A1 | |
| SCHEMBL13414068 | 0.81 | PLAU (0.46) | KMT2APLA2G2ATP53POLBCASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1739151-B1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GMBH (DE) | 2010-09-15 | — | — | EP | disclosed |
| EP-1739151-A1 | Mesogenic compounds, liquid crystal medium and liquid display | MERCK PATENT GmbH (DE) | 2007-01-03 | — | — | EP | disclosed |