Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229764 | 0.80 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL3720948 | 0.76 | ALDH1A1 (0.49) | SMN1; SMN2ALDH1A1MAPK1KMT2AHTT | |
| SCHEMBL5588267 | 0.71 | PPARG (0.42) | SMN1; SMN2ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL6262091 | 0.69 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL9236631 | 0.67 | KDM4E (0.35) | SMN1; SMN2ALDH1A1MAPK1MEN1KMT2A | |
| SCHEMBL1178613 | 0.66 | LMNA (0.42) | SMN1; SMN2ALDH1A1MAPK1KMT2AHTT | |
| SCHEMBL6233682 | 0.65 | ALOX5 (0.40) | MEN1KMT2A | |
| SCHEMBL5588269 | 0.65 | ESR1 (0.42) | SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6257613 | 0.65 | S1PR4 (0.39) | SMN1; SMN2ALDH1A1HTTHCRTR1HCRTR2 | |
| SCHEMBL9874009 | 0.64 | LMNA (0.50) | SMN1; SMN2ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010078906-A2 | HYDRAZIDES METHOD FOR PRODUCTION AND USE THEREOF AS HERBICIDE AND INSECTICIDE | BAYER CROPSCIENCE AG (DE) | 2010-07-15 | — | — | WO | disclosed |