SCHEMBL322998

SCHEMBL322998

O=C(OC(=O)c1ccccc1C(=O)OC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.58
F2 P00734 1/20 0.58
TSHR P16473 5/20 0.54
SLC6A3 Q01959 2/20 0.48
TDP1 Q9NUW8 3/20 0.48
TP53 P04637 1/20 0.48
ALDH1A1 P00352 5/20 0.47
KMT2A Q03164 3/20 0.47
MAPT P10636 2/20 0.47
MAPK1 P28482 1/20 0.47
HIF1A Q16665 1/20 0.47
POLB P06746 1/20 0.47
SLC6A2 P23975 1/20 0.47
AKR1C3 P42330 1/20 0.46
CES2 O00748 2/20 0.46
CES1 P23141 2/20 0.46
DAO P14920 1/20 0.46
NAPRT Q6XQN6 1/20 0.46
ALOX15 P16050 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29055923 0.98 LMNA (0.56) LMNAF2TSHRSLC6A3TDP1
SCHEMBL3822911 0.94 ALDH1A1 (0.58) LMNAF2TSHRSLC6A3TDP1
SCHEMBL28132113 0.92 ALDH1A1 (0.56) LMNAF2TSHRSLC6A3TDP1
Benzene SCHEMBL27793442 0.90 LMNA (0.70) LMNAF2TSHRSLC6A3TDP1
Hydrogen Peroxide SCHEMBL27952375 0.90 LMNA (0.70) LMNAF2TSHRSLC6A3TDP1
SCHEMBL52413 0.90 LMNA (0.70) LMNAF2TSHRSLC6A3TDP1
SCHEMBL27618276 0.90 TSHR (0.50) LMNAF2TSHRSLC6A3TDP1
Alcohol SCHEMBL4578564 0.90 TSHR (0.52) LMNAF2TSHRSLC6A3TDP1
SCHEMBL108624 0.89 TSHR (0.52) LMNAF2TSHRTP53ALDH1A1
SCHEMBL5183644 0.89 ALDH1A1 (0.58) LMNAF2TSHRALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 398 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023095183-A1 A PHARMACEUTICAL COMPOSITION AND A SOLID DOSAGE FORM THEREOF JORDAN UNIVERSITY OF SCIENCE AND TECHNOLOGY (JO) 2023-06-01 WO claimed
US-20230135608-A1 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE AS AN ACTIVE INGREDIENT PROVIDES A SPECIFIC PHARMACOKINETIC PARAMETER CURACLE CO., LTD. (KR) 2023-05-04 US claimed
US-20230058942-A1 EXTENDED RELEASE MULTIPARTICULATES OF RANOLAZINE SUN PHARMACEUTICAL IND LTD (IN) 2023-02-23 US claimed
CN-113645962-A Enteric coated tablet containing dimethyl fumarate 库拉科有限公司 2021-11-12 CN claimed
US-20210228488-A1 EXTENDED RELEASE COMPOSITIONS AND PROCESS FOR PREPARATION RUBICON RES PRIVATE LIMITED (IN) 2021-07-29 US claimed
US-20210106537-A1 EXTENDED RELEASE MULTIPARTICULATES OF RANOLAZINE SUN PHARMACEUTICAL IND LTD (IN) 2021-04-15 US claimed
US-10898444-B2 Extended release multiparticulates of ranolazine SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) 2021-01-26 US claimed
WO-2020242132-A1 ENTERIC TABLET CONTAINING DIMETHYL FUMARATE 주식회사 큐라클 2020-12-03 WO claimed
EP-1898886-B1 NOVEL SUSTAINED RELEASE DOSAGE FORM RUBICON RES PVT LTD (IN) 2019-09-04 EP claimed
US-20190262268-A1 ORAL MODIFIED RELEASE FORMULATIONS RUBICON RES PRIVATE LIMITED (IN) 2019-08-29 US claimed
US-5874582-A REACTING BENZOYL PHTHALIC ACID OR ESTER OR ANHYDRIDE DERIVATIVES WITH HYDROXYQUINOLINE DERIVATIVES; USEFUL FOR BULK DYEING PLASTICS; HEAT RESISTANCE, COLORFASTNESS AND WEATHERPROOFING BAYER AKTIENGESELLSCHAFT (DE) 1999-02-23 US claimed
CN-1197083-A Bulk dyeing process using quinolone derivative dyes BAYER AG (DE) 1998-10-28 CN claimed
EP-0870752-A1 Bulk dyeing using quinophthalone dyestuffs BAYER AG (DE) 1998-10-14 EP claimed
EP-0754452-A2 Pharmaceutical preparation in form of coated capsule releasable at lower part of digestive tract TANABE SEIYAKU CO., LTD. (JP) 1997-01-22 EP claimed
EP-0122815-B1 ENTERIC-SOLUBLE PREPARATIONS AND A PROCESS FOR THEIR PRODUCTION SANKYO COMPANY LIMITED (JP) 1989-10-25 EP claimed
EP-0108504-B1 A PROCESS FOR COATING SOLID PHARMACEUTICAL PREPARATIONS AND COATED PREPARATIONS THUS OBTAINED SANKYO COMPANY LIMITED (JP) 1987-05-13 EP claimed
US-4661162-A MIXTURE OF POLYMER WITH POLYANIONIC POLYMER WHICH IS SOLUBLE AT LOW PH SANKYO COMPANY, LIMITED (JP) 1987-04-28 US claimed
US-4497847-A MONO AND DIESTERS OF GLYCEROL AND SATURATED CARBOXYLIC ACIDS AS PLASTICIZERS SANKYO COMPANY, LIMITED (JP) 1985-02-05 US claimed
EP-0122815-A1 Enteric-soluble preparations and a process for their production SANKYO COMPANY LIMITED (JP) 1984-10-24 EP claimed
EP-0108504-A1 A process for coating solid pharmaceutical preparations and coated preparations thus obtained SANKYO COMPANY LIMITED (JP) 1984-05-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230135608-A1 PHARMACEUTICAL COMPOSITION CONTAINING DIMETHYL FUMARATE AS AN ACTIVE INGREDIENT PROVIDES A SPECIFIC PHARMACOKINETIC PARAMETER SLC5A2, FH, SLC5A1 LMNA 4052/4885F2 259/4885TSHR 4784/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.