SCHEMBL3230407

SCHEMBL3230407

C=C(CC(C)CC)C(N)=O

nearest known ligand 0.37

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.36
CA1 P00915 2/20 0.33
CA2 P00918 2/20 0.33
CA7 P43166 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GRIK1 P39086 1/20 0.31
GRIK2 Q13002 1/20 0.31
GRM1 Q13255 1/20 0.31
GRM2 Q14416 1/20 0.31
ELANE P08246 1/20 0.30
LAP3 P28838 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17183769 0.83 TSHR (0.39) TDP1CA1CA2GRIK1GRIK2
SCHEMBL13561365 0.81 TSHR (0.30)
SCHEMBL176067 0.80 BHMT (0.38) TDP1GRIK1GRIK2GRM1GRM2
SCHEMBL9468089 0.80 TDP1 (0.42) TDP1GRIK1GRIK2GRM1GRM2
SCHEMBL22952 0.79 TET2 (0.48) CA1CA2CA7CA14GRIK1
SCHEMBL21115790 0.79 ALDH1A1 (0.35) TDP1CA1CA2CA7CA14
SCHEMBL17183682 0.79 TDP1 (0.38) TDP1CA1CA2GRIK1GRIK2
SCHEMBL732388 0.78 TDP1 (0.33) TDP1
SCHEMBL17183761 0.78 TDP1 (0.33) TDP1CA1CA2
SCHEMBL913310 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4518865-A1 METHODS OF TREATING NEUROINFLAMMATORY CONDITIONS Athira Pharma, Inc. (US) 2025-03-12 EP disclosed
EP-4518866-A1 METHODS OF TREATING FIBROSIS Athira Pharma, Inc. (US) 2025-03-12 EP disclosed
EP-4518864-A1 METHODS OF TREATING NEUROPATHIES Athira Pharma, Inc. (US) 2025-03-12 EP disclosed
EP-4448100-A1 USES OF BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES Athira Pharma, Inc. (US) 2024-10-23 EP disclosed
CN-117986441-A Oil displacement agent for improving recovery ratio of low-permeability sensitive heavy oil reservoir and preparation method thereof 中国石油化工股份有限公司 2024-05-07 CN disclosed
WO-2023215377-A1 METHODS OF TREATING NEUROINFLAMMATORY CONDITIONS ATHIRA PHARMA, INC. (US) 2023-11-09 WO disclosed
WO-2023215376-A1 METHODS OF TREATING NEUROPATHIES ATHIRA PHARMA, INC. (US) 2023-11-09 WO disclosed
WO-2023215378-A1 METHODS OF TREATING FIBROSIS ATHIRA PHARMA, INC. (US) 2023-11-09 WO disclosed
EP-4236944-A1 BICYCLIC COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF DISEASES Athira Pharma, Inc. (US) 2023-09-06 EP disclosed
WO-2023114456-A1 USES OF BICYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES ATHIRA PHARMA, INC. (US) 2023-06-22 WO disclosed
WO-2022094400-A1 BICYCLIC COMPOUNDS AND USES THEREOF FOR THE TREATMENT OF DISEASES ATHIRA PHARMA, INC. (US) 2022-05-05 WO disclosed
US-20200223125-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE & TECH AGENCY (JP) 2020-07-16 US disclosed
US-20150298387-A1 RESIN FOR NANOIMPRINTING, LAMINATE CONTAINING RESIN FOR NANOIMPRINTING, PRINTED BOARD CONTAINING RESIN FOR NANOIMPRINTING, AND METHOD FOR PRODUCING NANOIMPRINT SUBSTRATE JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) 2015-10-22 US disclosed
US-8303943-B2 Ampholytic copolymer based on quaternized nitrogen-containing monomers BASF SE (DE) 2012-11-06 US disclosed
CN-101516934-B Amphoteric copolymers based on quaternized nitrogen-containing monomers BASF SE 2012-07-18 CN disclosed
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2010-03-18 US disclosed
EP-2064253-B1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2009-11-18 EP disclosed
WO-2009103735-A1 COMPOSITION CONTAINING AN AMPHOLYTIC COPOLYMER ON THE BASIS OF QUATERNISED MONOMERS CONTAINING NITROGEN AND AT LEAST ONE POLYMER THAT DIFFERS FROM SAID COPOLYMER, AND USE THEREOF BASF SE (DE) 2009-08-27 WO disclosed
EP-2064253-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2009-06-03 EP disclosed
WO-2008031892-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS BASF SE (DE) 2008-03-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068156-A1 AMPHOLYTIC COPOLYMER BASED ON QUATERNIZED NITROGEN-CONTAINING MONOMERS NGLY1, NAAA, NIT2 TDP1 1288/4885CA1 468/4885CA2 36/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.