Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TOP2A | P11388 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2387381 | 0.99 | MEN1 (0.51) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL5903459 | 0.92 | NPC1 (0.53) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL4199194 | 0.86 | HTR7 (0.48) | MEN1KMT2AL3MBTL1HTR7SIGMAR1 | |
| SCHEMBL4189060 | 0.84 | HTR7 (0.49) | L3MBTL1HTR7LMNASIGMAR1 | |
| SCHEMBL19623614 | 0.82 | MEN1 (0.52) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL13164567 | 0.82 | RECQL (0.67) | MEN1KMT2AKDM4ELMNARECQL | |
| SCHEMBL2459191 | 0.82 | MEN1 (0.52) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL25522780 | 0.82 | MEN1 (0.52) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| Hydrochloric Acid SCHEMBL2460354 | 0.82 | NCF1 (0.57) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL3222264 | 0.81 | CD274 (0.55) | MEN1KMT2AKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | claimed |
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | claimed |
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | claimed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | claimed |
| EP-1575538-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| WO-2004058201-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | disclosed |
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2010-03-18 | — | — | US | disclosed |
| EP-2050749-A1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-22 | — | — | EP | disclosed |
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | disclosed |
| US-7135047-B2 | M-phenylenediamine derivatives as coupler components for the coloring of keratinic fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-11-14 | — | — | US | disclosed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | disclosed |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-01-26 | — | — | US | disclosed |
| EP-1575538-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | disclosed |
| WO-2004058201-A1 | NOVEL M- PHENYLENDIAMINE DERIVATIVES AS COUPLER COMPONENTS FOR THE COLOURING OF KERATIN FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100069629-A1 | PYRIMIDINE DERIVATIVES AS PI3K INHIBITOR AND USE THEREOF | PIK3CA, AKT3, AKT1 | MEN1 2881/4885KMT2A 2799/4885KDM4E 2852/4885 |
| US-20060016023-A1 | Novel m-phenylenediamine derivatives as coupler components for the colouring of keratin fibres | KRT18, VIM, TPM4 | MEN1 1295/4885KMT2A 623/4885KDM4E 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.