Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | CCR8 | P51685 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.38 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | KMO | O15229 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1270728 | 0.85 | LMNA (0.47) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL11223738 | 0.83 | PLAU (0.44) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL27715437 | 0.81 | NPC1 (0.47) | MEN1KMT2AKDM4ERAB9ANPC1 | |
| SCHEMBL246279 | 0.78 | LOXL2 (0.36) | CCR1CCR5CCR8MEN1KMT2A | |
| SCHEMBL2921978 | 0.77 | KDM4C (0.41) | KDM4EALDH1A1TP53KMOSMN1; SMN2 | |
| SCHEMBL10765404 | 0.77 | KDM4E (0.33) | KDM4EALDH1A1SMN1; SMN2 | |
| Water SCHEMBL8053672 | 0.77 | LOXL2 (0.36) | CCR1CCR5CCR8MEN1KMT2A | |
| SCHEMBL18917198 | 0.77 | CYP2C19 (0.39) | KMT2AALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL14344868 | 0.76 | PLAU (0.44) | UHRF1CCR1CCR5CCR8MEN1 | |
| SCHEMBL15992556 | 0.75 | TDP1 (0.47) | UHRF1CCR1CCR5CCR8MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010009847-A1 | HETEROCYCLICALLY SUBSTITUTED AMIDES, METHOD FOR THE PRODUCTION THEREOF, AND USE AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2010-01-28 | — | — | WO | disclosed |
| EP-2147919-A1 | Heterocyclic substituted amides, method for their manufacture and their use as herbicides | Bayer CropScience Aktiengesellschaft (DE) | 2010-01-27 | — | — | EP | disclosed |